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Echocardiographic Assessment of Cardiovascular Changes in Long Term Space Flight

NCT00598598 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 1

Last updated 2017-01-12

No results posted yet for this study

Summary

The National Space Biomedical Research Institute is interested in learning more about heart function in space. One potential problem with long duration, manned space flight is muscle loss- including loss of heart muscle. One goal of our research is to help identify why this muscle loss occurs. We are interested in patients undergoing aortic valve surgery because this procedure is performed to correct a problem with the valve that may also change heart function. This change in heart function may provide information that is useful in understanding and potentially preventing the loss of cardiac muscle in space.

Three patient groups will be studied, patients having surgery for aortic regurgitation, aortic stenosis, and coronary bypass. We are planing to perform this study on 30 patients, 10 in each group.

The aim of this study is to continue our ongoing study of the magnitude and predictors of the changes in size of the left ventricle following acute volume and pressure unloading as a ground-based analog for manned space flight.

Conditions

  • Aortic Valve Insufficiency
  • Aortic Valve Stenosis

Sponsors & Collaborators

  • National Space Biomedical Research Institute

    collaborator OTHER

  • The Cleveland Clinic

    lead OTHER

Principal Investigators

  • Jim Thomas, MD · The Cleveland Clinic

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2003-10-31
Primary Completion
2008-06-30
Completion
2008-07-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00598598 on ClinicalTrials.gov