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Multi- Level and Integrated Analysis of Mechanisms Underlying Atrial Dysfunction

NCT02789943 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 750

Last updated 2017-04-06

No results posted yet for this study

Summary

Integrated and cross-disciplinary analysis of human physiology and disease provides unbiased and deeply informative insights into human health and disease. In this study the investigators will recruit patients undergoing coronary artery bypass surgery to study the atrium of the heart or the aortic wall that when diseased can cause strokes.

Hypothesis: Systems-level analysis of the left atrium and aorta cells that integrates imaging, histological, cellular and molecular data will identify new mechanism for cardiovascular form and function.

Conditions

  • Ischemic Heart Disease

Interventions

PROCEDURE

Cardiac Bypass Surgery

elective cardiac bypass surgery during which a sample of right atrial appendage and/ or aortic button can be removed

Sponsors & Collaborators

  • Duke-NUS Graduate Medical School

    collaborator OTHER

  • National Heart Centre Singapore

    lead OTHER

Principal Investigators

  • Stuart Alexander Cook · National Heart Centre Singapore / Duke NUS Graduate Medical School

Eligibility

Min Age
21 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2013-05-31
Primary Completion
2017-07-31
Completion
2021-04-30

Countries

  • Singapore

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02789943 on ClinicalTrials.gov