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Diagnostic Three Dimensional Echocardiography Study Protocol

NCT00598754 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2017-01-11

No results posted yet for this study

Summary

The purpose of this study is to perform ground-based research to study what happens to the heart muscle in space. People who have problems with their aortic valve have an increase in the amount of muscle in the left ventricle of the heart. After valve surgery, the amount of muscle should decrease and return to normal. Astronauts lose heart muscle mass during space flight. Our study will look at these changes in your heart, which we believe are similar to what happens during long term space travel.

This study will look at the accuracy of three dimensional ultrasound imaging (echo) in monitoring the changes in heart size and function following aortic valve replacement. We are studying ways to prevent health-related problems that men and women will face on long-duration space missions.

The hypothesis is that serial two dimensional and three dimensional echo will show accurate changes in the left ventricle mass and volume following aortic valve replacement for aortic stenosis or regurgitation

Conditions

  • Aortic Valve Stenosis
  • Aortic Valve Insufficiency

Sponsors & Collaborators

  • National Space Biomedical Research Institute

    collaborator OTHER

  • The Cleveland Clinic

    lead OTHER

Principal Investigators

  • Jim D Thomas, MD · The Cleveland Clinic

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2001-06-30
Primary Completion
2008-06-30
Completion
2008-07-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00598754 on ClinicalTrials.gov