Multi-Organ Screening Recommendations in Patients With Lynch Syndrome
NCT00582296 · Status: ACTIVE_NOT_RECRUITING · Type: OBSERVATIONAL · Enrollment: 1530
Last updated 2026-01-07
Summary
The purpose of this study is to examine how people with a family history of colon cancer and other related cancers respond to recommendations for cancer screening after genetic counseling. The purpose of your participation would be to help us learn more about whether people with a personal and/or family history of colorectal cancer and other cancers follow cancer screening recommendations.
Conditions
Interventions
- BEHAVIORAL
-
questionnaires, telephone interview, optional blood drawn
Initial CGS Visit (All Prospective Participants)Clinical assessment (screening, family \& personal history of CA, surgeries) 6 Month Follow-Up Phone Interview (Prospective) Follow-Up Questionnaire (prospective and retrospective) Retrospective Initial Interview Participants may also donate an additional blood, serum, saliva, urine, or stool sample for research, (in addition to the blood drawn for clinical testing) or for the sole purpose of research testing (in absence of clinical testing or prior external testing).
- BEHAVIORAL
-
questionnaires, telephone interview and optional blood drawn
Initial CGS Visit (All Prospective Participants)Clinical assessment (screening, family \& personal history of CA, surgeries) 6 Month Follow-Up Phone Interview (Prospective) Follow-Up Questionnaire (prospective and retrospective) Retrospective Initial Interview Participants may also donate an additional blood, serum, saliva, urine, or stool sample for research, (in addition to the blood drawn for clinical testing) or for the sole purpose of research testing (in absence of clinical testing or prior external testing).
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Albert Einstein College of Medicine
collaborator OTHER -
Memorial Sloan Kettering Cancer Center
lead OTHER
Principal Investigators
-
Zsofia Stadler, MD · Memorial Sloan Kettering Cancer Center
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-12-31
- Primary Completion
- 2026-12-31
- Completion
- 2026-12-31
Countries
- United States
Study Locations
More Related Trials
-
Germline Alterations of Tumor Susceptibility Genes in New York Cancer Patients
NCT00579514 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Clinical Genetics Branch Eligibility Screening Survey
NCT07005297 ·Status: NOT_YET_RECRUITING
-
Detection of Oncogenic Tumor Mutations in the Urine and Blood of Lung and Colorectal Cancer Patients
NCT02186236 ·Status: COMPLETED
-
A Social Media Approach to Improve Genetic Risk Communication Phase I
NCT01645904 ·Status: UNKNOWN
-
Ascertainment of Peripheral Blood or Saliva Samples for Genetic Epidemiology Studies of Familial Cancers
NCT00579163 ·Status: ACTIVE_NOT_RECRUITING
-
Lynch Syndrome Can be Diagnosed Just From Somatic Mismatch Repair Mutation
NCT04516083 ·Status: UNKNOWN
-
Lynch Syndrome X-Talk of Enteral Mucosa With Immune System
NCT06708429 ·Status: RECRUITING
-
Frequency of Endometrial Cancer Precursors Associated with Lynch Syndrome
NCT05257057 ·Status: COMPLETED
-
Web-based Family History Tool
NCT04890327 ·Status: COMPLETED ·Phase: NA
-
Cascade Genetic Testing for Hereditary Breast/Ovarian Cancer and Lynch Syndrome in Switzerland
NCT03124212 ·Status: RECRUITING
-
DNA Repair and Genetic Susceptibility to Lung Cancer
NCT00611598 ·Status: COMPLETED
-
Provider-Mediated Communication of Genetic Testing Results to At-Risk Relatives of Cancer Patients to Improve Genetic Counseling and Testing Rates, Family HOPE Study
NCT05772130 ·Status: RECRUITING ·Phase: NA
-
Patient Centered Clinical Decision Support for Hereditary Cancer Syndromes
NCT06914726 ·Status: ENROLLING_BY_INVITATION ·Phase: NA
-
Familial Investigations of Childhood Cancer Predisposition
NCT03050268 ·Status: RECRUITING
-
Molecular Screening for Lynch Syndrome in Southern Denmark
NCT01216930 ·Status: COMPLETED
-
Genetic Susceptibility to Lung Cancer in Never Smokers
NCT00597636 ·Status: ACTIVE_NOT_RECRUITING
-
Oncology Research Information Exchange Network in Improving Genetic Screening Rate in Patients With Cancer
NCT03348137 ·Status: WITHDRAWN
-
Overcoming Barriers to the Uptake of Cascade Screening for Lynch Syndrome: Workbook Feasibility Study
NCT04978350 ·Status: COMPLETED ·Phase: NA
-
Implementation of the Families Accelerating Cascade Testing Toolkit (FACTT) for Hereditary Breast and Ovarian Cancer and Lynch Syndrome
NCT04508764 ·Status: TERMINATED ·Phase: NA
-
Connecting Black Families in Houston, Texas to Hereditary Cancer Genetic Counseling, Genetic Testing, and Cascade Testing by Using a Simple Genetic Risk Screening Tool and Telegenetics
NCT05694559 ·Status: RECRUITING ·Phase: NA
-
Interest and Impact of Skin Cancer Genetic Testing
NCT02941900 ·Status: COMPLETED
-
Physicians Survey on Genetic Testing
NCT00341107 ·Status: COMPLETED
-
Lynne Cohen Consortium Project: Multi-Center Database/Registry
NCT00776958 ·Status: COMPLETED
-
Ascertainment of Saliva or Blood Samples For Genetic Epidemiology Studies of Cancer and Aging
NCT00579618 ·Status: COMPLETED
-
Detection of Germline and Somatic Pathogenic Variants in Patients With de Novo Metastatic Breast Cancer
NCT05758948 ·Status: UNKNOWN