A Community Study of the Risk for Obstructive Sleep Apnea and Respiratory Inflammation in an Adult Chinese Population
NCT04832711 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1270
Last updated 2024-10-22
Summary
We aimed to investigate the relationship between obstructive sleep apnea (OSA) risk and respiratory inflammation evaluated by the exhaled breath condensate (EBC)interleukin-6 IL-6 and plasma SP-D, based on the Berlin questionnaire (BQ) screening values in an adult, urban community in Beijing, China.
Volunteers aged \>40 years were recruited from the Shichahai community of central Beijing. Their general information and disease history were recorded. OSA risk was assessed using the BQ. IL-6 in EBC and plasma SP-D were detected by enzyme-linked immunoassay (ELISA)through specimens collected on fasting. The differences in IL-6 and SP-D contents between high-risk and low-risk groups for OSA were compared, and the factors affecting their contents were analyzed.
Conditions
- Obstructive Sleep Apnea
- Inflammation
- Exhaled Breath Condensate
- Surveys and Questionnaires
Sponsors & Collaborators
-
Peking University First Hospital
lead OTHER
Eligibility
- Min Age
- 40 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2009-05-31
- Primary Completion
- 2012-12-31
- Completion
- 2020-12-31
Countries
- China
Study Locations
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