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Volatile Anesthetics in Cardiac Protection

NCT00364637 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL

Last updated 2025-02-04

No results posted yet for this study

Summary

Patients undergoing stenting procedures, or cardiac or non-cardiac surgery could develop myocardial damage as testified by cardiac troponin release.

Sevoflurane (volatile anesthetic), routinely used in cardiac and non-cardiac anesthesia, has cardioprotective properties that could be useful to reduce cardiac damage, as indicated by cardiac troponin release in different contexts:

* stenting procedures (periprocedural administration)
* non-cardiac surgery (during the whole procedure)
* cardiac surgery (during the whole procedure)

Conditions

  • Anesthesia

Interventions

DRUG

Sevoflurane (Volatile Anesthetic)

DRUG

Total intravenous anesthesia

Sponsors & Collaborators

  • Università Vita-Salute San Raffaele

    lead OTHER

Principal Investigators

  • Giovanni Landoni, MD · Università Vita-Salute San Raffaele, Milano, Italia e Istituto Scientifico San Raffaele, Milano, Italia

  • Alberto Zangrillo, MD · Università Vita-Salute San Raffaele, Milano, Italia e Istituto Scientifico San Raffaele, Milano, Italia

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
100 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-01-31
Primary Completion
2024-08-24
Completion
2024-09-24

Countries

  • Italy

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00364637 on ClinicalTrials.gov