Efficacy Study for Treatment of Dementia in Progressive Supranuclear Palsy
NCT00522015 · Status: UNKNOWN · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 20
Last updated 2008-02-18
Summary
to show that
1. patients improve and stabilize after 12 -24 week treatment with rivastigmine in memory function
2. use of rivastigmine has a positive effect on apathy in PSP patients
3. therapy with rivastigmine has a no positive benefit on speech and overall results of the MMST
4. changes in motor activity are associated with changes in language and overall results of the in MMST
Conditions
Interventions
- DRUG
-
rivastigmine
rivastigmine 6 mg up to 12 mg daily; Taken in two doses from 3 mg to 6 mg Rivastigmine twice a day
Sponsors & Collaborators
-
University Hospital Tuebingen
lead OTHER
Principal Investigators
-
Daniela Berg, Doctor · University Hospital Tuebingen
Study Design
- Allocation
- NA
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2008-02-29
- Primary Completion
- 2009-12-31
- Completion
- 2010-02-28
Countries
- Germany
Study Locations
More Related Trials
-
Evaluation of the Efficacy of Rasagiline in Apathy in Drug-naïve Patients With Parkinson's Disease by a Multi-center Study
NCT01765257 ·Status: UNKNOWN ·Phase: PHASE4
-
The Effects of the Rivastigmine Patch on Parkinson's Disease With Memory and/or Thinking Problems
NCT00988117 ·Status: COMPLETED ·Phase: PHASE4
-
An Extension Study to Assess the Safety, Tolerability and Efficacy of ABT-SLV187 in Subjects With Advanced Parkinson's Disease and Persistent Motor-Complications Despite Optimized Treatment With Available Anti-Parkinsonian Medications
NCT02082249 ·Status: COMPLETED ·Phase: PHASE3
-
Study to Evaluate the Safety and Efficacy of Davunetide for the Treatment of Progressive Supranuclear Palsy
NCT01110720 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Efficacy, Tolerability and Safety of Azilect in Subjects With Progressive Supranuclear Palsy
NCT01187888 ·Status: TERMINATED ·Phase: PHASE3
-
Parallel-Group Study to Assess the Effect of Rasagiline on Cognition in Patients With Parkinson's Disease
NCT01723228 ·Status: COMPLETED ·Phase: PHASE4
-
Rotigotine Versus Placebo to Evaluate the Efficacy on Depressive Symptoms in Idiopathic Parkinson's Disease Patients
NCT01523301 ·Status: COMPLETED ·Phase: PHASE4
-
Extension Study of ABBV-8E12 in Patients With Progressive Supranuclear Palsy (PSP) Who Completed Study C2N-8E12-WW-104
NCT03413319 ·Status: COMPLETED ·Phase: PHASE1
-
Non Motors Aspects in De Novo Parkinson's Disease
NCT02786667 ·Status: UNKNOWN ·Phase: PHASE3
-
Open Label Extension Study To Investigate Long Term Safety, Tolerability And Efficacy Of Pf-02545920 In Subjects With Huntington's Disease Who Completed Study A8241021
NCT02342548 ·Status: TERMINATED ·Phase: PHASE2
-
The Progressive Supranuclear Palsy Clinical Trial Platform - Regimen B: LM11A-31
NCT07264283 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2
-
Study of Rivastigmine to Treat Parkinsonian Apathy Without Dementia
NCT00767091 ·Status: COMPLETED ·Phase: PHASE3
-
Pioglitazone in Early Parkinson's Disease
NCT01280123 ·Status: COMPLETED ·Phase: PHASE2
-
Rasagiline and Apathy in Parkinson's Disease
NCT00755027 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Test the Safety and Tolerability of UCB0107 in Study Participants With Progressive Supranuclear Palsy (PSP)
NCT04185415 ·Status: COMPLETED ·Phase: PHASE1
-
Long-term Safety of Rivastigmine Capsule and Patch in Patients With Mild to Moderately-severe Dementia Associated With Parkinson's Disease (PDD)
NCT00623103 ·Status: COMPLETED ·Phase: PHASE3
-
Safety, Tolerability, and Pharmacokinetics of C2N-8E12 in Subjects With Progressive Supranuclear Palsy
NCT02494024 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Rotigotine on Motor Symptoms in Patients With Advanced Parkinson's Disease (PD) With Motor Fluctuations and Symptoms of Gastrointestinal Dysfunction
NCT01536015 ·Status: TERMINATED ·Phase: PHASE3
-
A Study to Assess Efficacy, Safety, Tolerability, and Pharmacokinetics of ABBV-8E12 in Subjects With Progressive Supranuclear Palsy (PSP)
NCT02985879 ·Status: TERMINATED ·Phase: PHASE2
-
A Study to Assess Tolerability, Safety, Pharmacokinetics and Effect of AZP2006 in Patients With PSP
NCT04008355 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Initial Effectiveness of Transcranial MR Guided Focused Ultrasound for the Treatment of Parkinson's Disease
NCT04002596 ·Status: COMPLETED ·Phase: NA
-
Study About Safety and Efficacy of Coenzyme Q10 in Progressive Supranuclear Palsy
NCT00328874 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of 2.5 Years of Rasagiline Therapy on Progression of Cognitive Biomarkers Assessed by MRI in Parkinson's Disease.
NCT02278588 ·Status: COMPLETED
-
Effects of Coenzyme Q10 in Progressive Supranuclear Palsy (PSP)
NCT00382824 ·Status: COMPLETED ·Phase: NA
-
A Phase 4, Open-label Study to Assess the Feasibility and Efficacy on Motor and Non-motor Symptoms of Switching From Pramipexole or Ropinirole to Rotigotine Transdermal Patch in Subjects With Advanced Idiopathic Parkinson's Disease
NCT01711866 ·Status: COMPLETED ·Phase: PHASE4