Sleep Apnea and Tromboembolic Disease
NCT00501358 · Status: UNKNOWN · Type: OBSERVATIONAL
Last updated 2007-07-16
Summary
There is some evidence for a hypercoagulable state in sleep apnea-hipopnea syndrome (SAHS), which could play a role in the increased cardiovascular morbility and mortality. Respiratory alterations (hypoxia, hypoxia- reoxygenation) and sleep fragmentation that these patients suffer during the sleep may induce modifications in clotting-fibrinolisis factors that may be a risk factor for venous thromboembolism (VTE).
OBJECTIVES:To calculate and compare the prevalence of sleep apnea-hipopnea syndrome in patients with venous thromboembolism with a gender, aged and BMI matched control group. Assessment of the association between SAHS and other risk factors for VTE. To compare clotting- fibrinolisis patterns, sleep parameters, blood pressure and pulmonary arterial obstruction index in patients with SAHS and VTE and those ones without SAHS.
Conditions
- Sleep Apnea Syndromes
- Venous Thromboembolism
Sponsors & Collaborators
-
Fundacion Caubet-Cimera Islas Baleares
collaborator OTHER -
Sociedad Española de Neumología y Cirugía Torácica
lead OTHER
Principal Investigators
-
Alberto Alonso, MD · Sociedad Española de Neumología y Cirugía Torácica
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
Countries
- Spain
Study Locations
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