Obstructive Sleep Apnea in Pulmonary Embolism
NCT01580085 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 75
Last updated 2012-04-18
Summary
Obstructive sleep apnea (OSA) is a clinical syndrome characterized by repetitive closure of the airway and frequent awakenings during sleep. Repeated episodes of hypoxia, decrease in intrathoracic pressure, increased venous return and venous stasis, damage to vascular wall may ensue. An increased tendency for coagulation has also been reported in OSA. Venous stasis, vascular endothelial activation and hypercoagulability are also known risk factors for thromboembolism. All of these pathophysiologic changes in OSA may predispose patients for the development of pulmonary embolism (PE) however there is limited data about role of thromboembolic events in OSA.
Conditions
- Pulmonary Thromboembolism
- Obstructive Sleep Apnea
Interventions
- OTHER
-
polysomnography
full night supervised laboratory polysomnography
Sponsors & Collaborators
-
University of Gaziantep
lead OTHER
Principal Investigators
-
Meral Uyar, Assist Prof · University of Gaziantep
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2009-11-30
- Primary Completion
- 2010-12-31
- Completion
- 2010-12-31
Countries
- Turkey (Türkiye)
Study Locations
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