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Study of Mechanisms of Anovulation in Polycystic Ovary Syndrome

NCT00492882 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 30

Last updated 2026-05-14

No results posted yet for this study

Summary

We previously hypothesized that the excess of Anti-Mullerian Hormone (AMH) at the level of ovarian selectable follicles could be involved in the follicular arrest of Polycystic Ovary Syndrome (PCOS), mainly through inhibition of FSH effect on aromatase expression.In this study, we plan to investigate whether a drop in the serum AMH level would be concomitant to the appearance of a dominant follicle induced by administration of mild amounts of exogenous FSH in women with PCOS.

Conditions

  • Anovulation

Interventions

DRUG

usual administration of exogenous recombinant FSH

Sponsors & Collaborators

  • Organon

    collaborator INDUSTRY

  • University Hospital, Lille

    lead OTHER

Principal Investigators

  • Didier R DEWAILLY, MD · University Hospital of Lille

Eligibility

Min Age
18 Years
Max Age
40 Years
Sex
FEMALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2003-11-30
Completion
2007-01-31

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00492882 on ClinicalTrials.gov