Measuring Blood Flow in the Brain

NCT00466934 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 31

Last updated 2017-07-02

No results posted yet for this study

Summary

This study will test a method of measuring brain blood flow called near infrared spectroscopy (NIRS). It will determine whether NIRS gives the same results as the more commonly used technique, functional magnetic resonance imaging (fMRI).

Healthy normal volunteers between 18 and 60 years of age may be eligible for this study. Participants come to the NIH up to six times for experiments using NIRS and fMRI. They do the following tasks while they are undergoing NIRS or fMRI:

* looking at a computer monitor while a checkerboard pattern changes
* wiggling the toes and moving the fingers
* Reading words on a computer screen and pushing one button if they are plants and another if they are animals.

For NIRS, a frame is placed on the head and held it in place with a metal band. The frame holds sensors that contact the scalp.

For fMRI, the subject lies on a table that can slide in and out of an MRI scanner, a metal cylinder surrounded by a strong magnetic field. fMRI uses a strong magnetic field and radio waves to obtain images of the brain while the subject performs tasks. During the procedure, The subject wears earplugs to muffle the sound of loud knocking noises that occur during scanning.

Conditions

Sponsors & Collaborators

  • United States Department of Defense

    collaborator FED
  • National Institutes of Health Clinical Center (CC)

    collaborator NIH
  • Center for Neuroscience and Regenerative Medicine (CNRM)

    collaborator FED
  • National Institute of Neurological Disorders and Stroke (NINDS)

    lead NIH

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2007-04-24
Completion
2011-12-29

Countries

  • United States

Study Locations

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Entities

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00466934 on ClinicalTrials.gov