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Atrial Substrate Modification With Aggressive Blood Pressure Lowering to Prevent AF

NCT00438113 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 184

Last updated 2017-06-20

No results posted yet for this study

Summary

Atrial fibrillation (AF) is a very common arrhythmia causing many symptoms resulting in numerous hospitalizations. Catheter ablation is a technique that has evolved significantly to improve symptomatic recurrences, but does not offer a 100% cure rate. We hypothesize that the use of aggressive BP lowering will reduce the rate of recurrent AF after catheter ablation for AF. We plan a randomized clinical trial of aggressive BP lowering versus standard BP control to investigate this.

Conditions

Interventions

DRUG

Aggressive Blood Pressure control

Aggressive Blood Pressure therapy, alone or combination therapy, to reach a target BP equal to or less than 120/80 mmHg

Sponsors & Collaborators

  • Nova Scotia Health Research Foundation

    collaborator OTHER_GOV

  • Nova Scotia Health Authority

    lead OTHER

Principal Investigators

  • Ratika Parkash, MD MSc · Dalhousie University/QEII HSC

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2009-12-31
Primary Completion
2016-09-30
Completion
2016-09-30

Countries

  • Canada

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00438113 on ClinicalTrials.gov