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Photographic Imaging of the Retina and Optic Nerve Head of Glaucoma Patients and Normal Controls

NCT00430274 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 120

Last updated 2017-08-25

No results posted yet for this study

Summary

Retinal structures are difficult to visualize because the retina is optically transparent. In glaucoma, the microglia in the retina becomes activated in eyes with glaucomatous damage. The microglia forms a dense meshwork which resembles gliosis-like alterations, which may increase light scattering. With appropriate technology, increased reflection and light scattering from the retina may be detected in eyes of glaucoma patients.

In this study, we investigate whether clinically observable retinal gliosis-like alterations occur more often in patients with glaucoma than in non-glaucomatous controls, and whether gliosis-like alterations are associated with a vasospastic propensity.

Conditions

Sponsors & Collaborators

  • Selim Orguel

    lead OTHER

Principal Investigators

  • Selim Orgül, MD · University Eye Clinic Basel

Eligibility

Min Age
45 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2006-01-31
Primary Completion
2009-08-31
Completion
2017-04-30

Countries

  • Switzerland

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00430274 on ClinicalTrials.gov