MedTrace Logo

Physical Fitness and Hot Executive Function in Alzheimer's Risk

NCT07081269 · Status: RECRUITING · Type: OBSERVATIONAL · Enrollment: 240

Last updated 2025-07-23

No results posted yet for this study

Summary

This 18-month study tracks how physical fitness relates to executive function in older adults, aiming to determine if fitness improvements predict better cognitive performance. Participants complete assessments at baseline and 18 months, including cardiorespiratory fitness (YMCA bike test), muscle strength (chest and leg press tests), and executive function (computer tasks with brain activity recording via EEG). Additional measures include physical activity questionnaires, cognitive screening (MMSE), memory tests (digit span), demographics (age, sex, education), and blood tests for APOE ε4 gene status. No exercise program will be provided, allowing observation of natural fitness-cognition relationships in daily life.

Conditions

  • Executive Function (Cognition)
  • Event-Related Potentials
  • Physical Fitness

Interventions

OTHER

observation alone

No interventions will be conducted during the observation period, maintaining participants' normal daily living conditions.

Sponsors & Collaborators

  • National Taiwan Normal University

    lead OTHER

Principal Investigators

  • Yu-Kai Chang, PhD · National Taiwan Normal University

  • Chine-Heng Chu, PhD · National Taiwan Normal University

Eligibility

Min Age
50 Years
Max Age
70 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-01-10
Primary Completion
2027-07-31
Completion
2027-07-31

Countries

  • Taiwan

Study Locations

More Related Trials

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT07081269 on ClinicalTrials.gov