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Correlations Between BNP & Dry Weight, and Between Troponin & Mortality, in Hemodialysis Patients

NCT00416013 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 151

Last updated 2010-10-07

No results posted yet for this study

Summary

Beta Natriuretic Peptide (BNP) is regarded as the most sensitive test for congestive heart failure (CHF). BNP has also been found to be highly predictive of other conditions including pulmonary hypertension, pulmonary embolism and in the general population where mild increases are associated with stroke and heart attack. BNP is also weakly and variably correlated with renal function.

We believe that each dialysis patient will have an ideal or "dry" BNP level which will accurately and reproducibly reflect their optimal fluid status. Secondary hypotheses are that baseline BNP and troponin, as well as changes in BNP and troponin during dialysis, will be highly predictive of mortality and adequacy of dialysis.

Conditions

  • Kidney Failure, Chronic
  • Heart Failure, Congestive

Sponsors & Collaborators

  • Abbott RDx Cardiometabolic

    collaborator OTHER

  • Eastern Virginia Medical School

    lead OTHER

Principal Investigators

  • Mark C Flemmer, MBB Ch · Eastern Virginia Medical School

Eligibility

Min Age
18 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-12-31
Completion
2010-12-31

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00416013 on ClinicalTrials.gov