Hemangioma Associated With High Rates of Morbidity

Summary

We are conducting a study on the possible presence of PHACES in children with large facial hemangiomas and lumbosacral hemangiomas of infancy (hemangioma in the lower back) . With this study we hope to better understand the risk of this syndrome and to develop guidelines for its evaluation and management.

Conditions

• Hemangioma

Interventions

DEVICE

MRI

MRI of the spine.

DEVICE

MRI of head and neck

MRI of head and C-spine

OTHER

Dermatological Examination

Complete dermatological examination to identify and characterize nature of dermatological anomalies

OTHER

Cardiac examination

Complete cardiac examination

DEVICE

Abdominal ultrasound

Abdominal ultrasound to detect hepatic hemangiomas

Sponsors & Collaborators

• University of California, San Francisco

  collaborator OTHER

• Columbia University

  collaborator OTHER

• Baylor College of Medicine

  collaborator OTHER

• St. Justine's Hospital

  collaborator OTHER

• State University of New York - Downstate Medical Center

  collaborator OTHER

• Children's Mercy Hospital Kansas City

  collaborator OTHER

• Children's Hospital Medical Center, Cincinnati

  collaborator OTHER

• Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

  collaborator OTHER

• Medical College of Wisconsin

  lead OTHER

Principal Investigators

• Beth Drolet, MD · Medical College of Wisconsin

• Maria Garzon, MD · Columbia University

• Denise Metry, MD · Baylor College of Medicine

• Ilona Frieden, MD · University of California, San Francisco

• Julie Powell, MD · Hopital Sainte-Justine

• Anne Lucky, MD · Children's Hospital of Cincinnati

• Sharon Glick, MD · State University of New York - Downstate Medical Center

• Eulalia Baselga, MD · Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau

• Anita Haggstrom, M.D. · Indiana University

• Anthony Mancini, MD · Northwestern University

• Kimberly Horii, MD · Children's Mercy Hospital Kansas City

Study Design

Allocation

NON_RANDOMIZED

Purpose

SCREENING

Masking

NONE

Model

SINGLE_GROUP

Eligibility

Max Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2005-11-30

Primary Completion

2009-11-30

Completion

2010-01-31

Countries

• United States

Study Locations