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Functional MRI Evaluation in Pyeloureteral Junction Syndrome in Children

NCT05498532 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 270

Last updated 2026-06-16

No results posted yet for this study

Summary

Pyelo-ureteral junction syndrome is the most common urological abnormality in children.

Functional MRI has been evaluated several times and has shown good correlation with scintigraphy, but tends to overestimate results. Moreover, those studies included a small number of cases. Its sensitivity to detect crossing polar vessels is limited.

The investigators aimed to evaluate, in patients between 0 and 1 year old, the correlation between MRI and scintigraphy differential renal function.

The secondary objectives are the evaluation of MRI performances to detect polar vessels; the comparison of surgery times depending on MRI-only realization or MRI and scintigraphy realization.

Conditions

  • Stricture of Pelviureteric Juncture

Interventions

DIAGNOSTIC_TEST

Functional MRI

Anatomical MRI : T2 fiesta, SSFE, HASTE ; 3D T2 ; T1 FAT SAT ; LAVA Functional MRI : T1 FAT SAT with gadolinium

Sponsors & Collaborators

  • Central Hospital, Nancy, France

    lead OTHER

Principal Investigators

  • Charles Mazeaud · CHRU Nancy

Eligibility

Min Age
1 Day
Max Age
17 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2022-09-01
Primary Completion
2022-09-15
Completion
2022-12-30

Countries

  • France

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT05498532 on ClinicalTrials.gov