Resuscitation Outcomes Consortium (ROC) Prehospital Resuscitation Using an Impedance Valve

Summary

The purpose of this study is to look at two different treatments during a cardiac arrest that occurs outside of the hospital and whether either or both treatments will increase the number of people who live to hospital discharge. A cardiac arrest is when the heart stops pumping blood to the body.

Conditions

• Heart Arrest

Interventions

DEVICE

Impedance Threshold Device (ITD)

Use of Impedance Threshold Device (ITD)

DEVICE

Sham ITD

Sham ITD

OTHER

Analyze early

Upon EMS arrival at the scene of a non-traumatic cardiac arrest, an assessment of the cardiac rhythm is done to determine whether a defibrillatory shock is required.

OTHER

Analyze later

Upon EMS arrival at the scene of a non-traumatic cardiac arrest, three minutes of CPR is given prior to the assessment of the cardiac rhythm to determine whether a defibrillatory shock is required.

Sponsors & Collaborators

• National Heart, Lung, and Blood Institute (NHLBI)

  collaborator NIH

• National Institute of Neurological Disorders and Stroke (NINDS)

  collaborator NIH

• Canadian Institutes of Health Research (CIHR)

  collaborator OTHER_GOV

• Defence Research and Development Canada

  collaborator INDUSTRY

• Heart and Stroke Foundation of Canada

  collaborator OTHER

• American Heart Association

  collaborator OTHER

• University of Washington

  lead OTHER

Principal Investigators

• Myron L Weisfeldt, MD · Johns Hopkins University

Study Design

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Model

FACTORIAL

Eligibility

Min Age

18 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2007-06-30

Primary Completion

2009-11-30

Completion

2010-07-31

Countries

• United States
• Canada

Study Locations