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Comparison of Side Effects of Morphine and Hydromorphone Patient-Controlled Analgesia (PCA)

NCT00385541 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 50

Last updated 2018-08-14

Study results available
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Summary

Both morphine and hydromorphone are pain medications commonly used after surgery. It is thought at the institution that hydromorphone causes less side effects but this has not been studied. The study proposes to treat the patients with either morphine or hydromorphone and determine how much nausea, vomiting, and itching they have with each drug

Conditions

  • Post Operative Pain

Interventions

DRUG

Morphine PCA

Morphine 1mg/mL, dose 1mL, lockout 6 minutes, max 10mL

DRUG

Hydromorphone PCA

hydromorphone PCA 0.2mg/lml, dose 1ml, lockout 6min, max 10ml

Sponsors & Collaborators

Principal Investigators

  • Pamela Flood, MD · Columbia University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
60 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2003-11-30
Primary Completion
2007-10-31
Completion
2007-10-31
FDA Drug
Yes

Countries

  • United States

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00385541 on ClinicalTrials.gov