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Titrated Versus High and Low Dose Nebulized Morphine to Reduce Pain in Emergency Settings

NCT02200185 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 300

Last updated 2014-12-02

No results posted yet for this study

Summary

The investigators test a different technique using morphine to improve pain relief in patient visiting the emergency department with acute trauma pain, for this we are comparing three different methods of morphine administration:

* intravenous titrated morphine
* low dose nebulized morphine and
* high dose nebulized morphine

Conditions

  • Post-Traumatic Headache
  • Acute Pain

Interventions

DRUG

IV titrated morphine

Intravenous morphine : 2 mg every 5 minutes by IV root and nebulized placebo: * SS nebulised : 5 ml SS nebulised over 10 minutes and repeated 3 times

DRUG

Low dose nebulised morphine

10 mg morphine in 4 ml Serum Saline(SS) nebulised over 10 minutes and repeated 3 times, and SS IV placebo : 2 ml by IV root every 5 minutes

DRUG

High dose nebulised morphine

20 mg morphine in 3 ml serum saline (SS) nebulised over 10 minutes and repeated 3 times, and SS IV placebo : 2 ml by IV root every 5 minutes

Sponsors & Collaborators

  • University of Monastir

    lead OTHER

Principal Investigators

  • Nouira Semir, Professor · University of Monastir

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
8 Years
Max Age
50 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2012-04-30
Primary Completion
2014-07-31
Completion
2014-07-31

Countries

  • Tunisia

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02200185 on ClinicalTrials.gov