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A Comparison of Two Anaesthetic Methods of Protecting Heart Tissue During Cardiac Surgery

NCT00244283 · Status: UNKNOWN · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 150

Last updated 2005-10-26

No results posted yet for this study

Summary

To compare two different methods of protecting heart muscle from damage caused by a decreased blood supply. Exposure to the anaesthetic agent sevoflurane can allow the heart muscle to resist longer periods of low blood or oxygen supply without sustaining the amount of damage that it would otherwise expect to. The use of thoracic epidural analgesia improves the blood flow to the heart muscle and has also been shown to reduce the amount of damage the heart muscle may otherwise sustain. The aim of this study is to compare these two methods.

Conditions

  • Coronary Artery Bypass Surgery

Interventions

DRUG

Sevoflurane

PROCEDURE

High thoracic epidural analgesia

Sponsors & Collaborators

  • European Society for Intravenous Anaesthesia

    collaborator OTHER

  • Golden Jubilee National Hospital

    lead OTHER_GOV

Principal Investigators

  • Stefan Schraag, MD PhD · Golden Jubilee National Hospital

  • Martin F McCormick, MB ChB · Golden Jubilee National Hospital

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
80 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2006-01-31
Completion
2008-01-31

Countries

  • United Kingdom

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00244283 on ClinicalTrials.gov