Effect of GTN and Diamox Measured by BOLD-Response.
NCT00363792 · Status: UNKNOWN · Phase: NA · Type: INTERVENTIONAL · Enrollment: 12
Last updated 2006-08-15
Summary
In healthy subjects different cerebral haemodynamic values wished to be determined after infusion of the NO donor Glyceryl trinitrate (GTN) and Diamox. The different values we wish to determine are:
* Blood-oxygenation-level-Dependent-signal (BOLD-signal) after visual stimulation.
* Changes in the diameter of a. cerebri media.
* Changes in the regional and global cerebral blodd flow (CBF) with the help of the arterial Spin labeling (ASL) method.
Conditions
- Healthy
Interventions
- DRUG
-
Glyceryl trinitrate, azetazolamide
Sponsors & Collaborators
-
Danish Headache Center
lead OTHER
Principal Investigators
-
Messoud Ashina, MD, Phd, · Danish Headache Center
Study Design
- Allocation
- RANDOMIZED
- Purpose
- ECT
- Masking
- DOUBLE
- Model
- CROSSOVER
Eligibility
- Min Age
- 18 Years
- Max Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Completion
- 2007-05-31
Countries
- Denmark
Study Locations
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