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Comparison of Dexmedetomidine and Fentanyl to Prevent Hemodynamic Response to Skull Pins Application

NCT03077503 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 60

Last updated 2020-08-20

No results posted yet for this study

Summary

To compare the effect between dexmedetomidine and fentanyl for controlling the hemodynamic response to skull pins application

Conditions

  • Hemodynamic Response
  • Skull Pins Application

Interventions

DRUG

Dexmedetomidine

Dexmedetomidine 1 µg/kg diluted to 20 ml with 0.9% normal saline was administration. If adverse events were occurred, the patient will receive rescue drugs.

DRUG

Fentanyl

Fentanyl 1 µg/kg diluted to 2 ml with 0.9% normal saline was administration. If adverse events were occurred, the patient will receive rescue drugs.

DRUG

0.9% normal saline

0.9% normal saline was use to dilute the study drugs

DEVICE

Skull pins

Skull pins were use to stabilized the patent' s head during surgery

Sponsors & Collaborators

  • Khon Kaen University

    lead OTHER

Principal Investigators

  • Pornthep Kasemsiri, MD · Khon Kaen University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Max Age
64 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2015-09-01
Primary Completion
2016-09-30
Completion
2016-09-30

Countries

  • Thailand

Study Locations

More Related Trials

Entities

Drugs

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT03077503 on ClinicalTrials.gov