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Effect of HBO on Functional Connectivity of Resting State Networks in Patients With Cerebral Small Vessel Disease

NCT02232958 · Status: TERMINATED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 20

Last updated 2017-10-30

No results posted yet for this study

Summary

The purpose of this study is to extend our previous work, in which we demonstrated an increase in the internal and cross network connectivity of resting state neural networks in patients with cerebral small vessel disease by treatment with hyperbaric oxygen, to at least 20 more individuals.

Conditions

  • Encephalopathy
  • White Matter Hyperintensities
  • Impaired Oxygen Delivery

Interventions

OTHER

Hyperbaric Oxygen Treatment

Patients are placed in a special chamber in which the pressure is gradually increased up to the desired pressure with 100% Oxygen and the patient is kept at that pressure for one hour. Then the Oxygen flow is slowly reduced until the patient has been returned to one atmosphere of pressure.

Sponsors & Collaborators

  • Washington University School of Medicine

    collaborator OTHER

  • St. Luke's Hospital, Chesterfield, Missouri

    lead OTHER

Principal Investigators

  • John D. Davidson, MD · St. Luke's Hospital St. Louis & Washington University Medical School

Study Design

Allocation
NA
Purpose
TREATMENT
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
50 Years
Max Age
90 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2014-09-16
Primary Completion
2016-05-24
Completion
2017-10-04

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02232958 on ClinicalTrials.gov