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Role of Sleep in Cardiovascular Functions

NCT04166916 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 71

Last updated 2025-05-16

No results posted yet for this study

Summary

Sleep and particularly deep sleep are playing an important role for brain and body health. Poor sleep has been associated with risk factors for cardiovascular disease and moreover, is hypothesized to increased mortality risk of cardiovascular diseases. Yet, the role of specific sleep processes for cardiovascular function remains unclear. Particularly deep sleep, which is manifested by large amplitude, low frequency oscillations is of importance for the restorative functions of sleep. Thus, the modulation of deep sleep by auditory stimulation will be of central interests to assess the cause-effect relationship of specific processes within sleep for cardiovascular regulation.

This study will assess the effects of slow wave modulating auditory stimulation on cardiovasuclar functions in healthy male participants.

Conditions

  • Sleep

Interventions

OTHER

Acoustic stimulation

Acoustic stimulation to modulate slow waves.

OTHER

SHAM acoustic stimulation

This is the sham-control intervention; only the biosignal will be recorded but no acoustic stimulation will be played.

Sponsors & Collaborators

  • Caroline Lustenberger

    lead OTHER

Principal Investigators

  • Caroline Lustenberger, PhD · ETH Zurich

Study Design

Allocation
RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
DOUBLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
84 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2020-01-13
Primary Completion
2021-03-11
Completion
2021-03-11

Countries

  • Switzerland

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04166916 on ClinicalTrials.gov