Interaction of Docetaxel and Lonafarnib in Patients With Advanced Cancer
NCT00288444 · Status: TERMINATED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 38
Last updated 2012-12-18
Summary
To determine the molecular interaction in tumor samples between docetaxel and lonafarnib.
Conditions
- Lung Cancer
- Soft Tissue Sarcoma
- Colorectal Carcinoma
- Breast Cancer
- Prostate Cancer
Interventions
- DRUG
-
Lonafarnib
- DRUG
Sponsors & Collaborators
-
Aventis Pharmaceuticals
collaborator INDUSTRY -
Schering-Plough
collaborator INDUSTRY -
Emory University
lead OTHER
Principal Investigators
-
John Kauh, MD · Emory University
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- PARALLEL
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-01-31
- Primary Completion
- 2008-05-31
- Completion
- 2009-03-31
Countries
- United States
Study Locations
More Related Trials
-
A Study of LY3214996 Administered Alone or in Combination With Other Agents in Participants With Advanced/Metastatic Cancer
NCT02857270 ·Status: COMPLETED ·Phase: PHASE1
-
Everolimus and Octreotide in Patients With Advanced Carcinoid Tumor
NCT00412061 ·Status: COMPLETED ·Phase: PHASE3
-
Phase 1 Clinical Trial to Evaluate the Safety and Anti-Tumor Activity of AB-201
NCT06341647 ·Status: WITHDRAWN ·Phase: PHASE1
-
A Study of LY2835219 (Abemaciclib) in Combination With Therapies for Breast Cancer That Has Spread
NCT02057133 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Study of MM-121 in Combination With Paclitaxel in Patients With Advanced Gynecologic and Breast Cancers
NCT01209195 ·Status: COMPLETED ·Phase: PHASE1
-
Phase Ib/II Study of MCS110 in Combination With PDR001 in Patients With Advanced Malignancies
NCT02807844 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
The Efficacy and Safety of CDK4/6 Inhibitors in Combination with Endocrine Therapy in the Neoadjuvant Treatment
NCT06810492 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Effects of Ribociclib and Palbociclib on Tumor and Blood Characteristics in Patients With Metastatic Breast Cancer
NCT05244434 ·Status: WITHDRAWN ·Phase: NA
-
Phase Ib/II Study of LY2780301 in Combination With Weekly PACLITAXEL in HER2-metastatic Breast Cancer
NCT01980277 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Study of the Combination of Axitinib Plus Everolimus in Patients With Malignant Advanced Solid Tumors
NCT01334073 ·Status: COMPLETED ·Phase: PHASE1
-
DS8201a and Pembrolizumab in Participants With Locally Advanced/Metastatic Breast or Non-Small Cell Lung Cancer
NCT04042701 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
A Study of LY2880070 in Participants With Advanced or Metastatic Cancer
NCT02632448 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
SNF Platform Study of HR+/ HER2-advanced Breast Cancer
NCT05594095 ·Status: RECRUITING ·Phase: PHASE2
-
A Study of LY3023414 in Participants With Advanced Cancer
NCT01655225 ·Status: COMPLETED ·Phase: PHASE1
-
Predicted Biomarkers of CDK4/6 Inhibitors (Palbociclib) in ER-positive Metastasis Breast Cancer
NCT04289974 ·Status: UNKNOWN
-
A Dose Increase Finding Study of Doxorubicin Hydrochloride Liposome Injection for Patients With Breast Cancer
NCT03017404 ·Status: COMPLETED ·Phase: NA
-
A Study of LCL161 in Combination With Weekly Paclitaxel in Adult Patients With Advanced Solid Tumors
NCT01240655 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Paclitaxel in Combination With BOS172722 in Patients With Advanced Nonhaematologic Malignancies
NCT03328494 ·Status: COMPLETED ·Phase: PHASE1
-
A Multicenter, Double-blind, Randomized, Parallel-group, Phase III Study of the Efficacy and Safety of QL1701 Plus Docetaxel Versus Herceptin® Plus Docetaxel as First Line Therapy in Patients With HER2-positive Metastatic Breast Cancer
NCT05629949 ·Status: COMPLETED ·Phase: PHASE3
-
Palbociclib in Combination With Adjuvant Endocrine Therapy for Hormone Receptor Positive, HER2 Negative Invasive Breast Cancer
NCT02040857 ·Status: COMPLETED ·Phase: PHASE2
-
Utilizing Multiomic Advanced Diagnostics to Identify CDK 4/6 Inhibitor Response Predictors and a Post-treatment Multiomic Signature for Patients With ER+/HER2- Metastatic Breast Cancer
NCT03195192 ·Status: COMPLETED ·Phase: NA
-
A Study of Abemaciclib (LY2835219) Combined With Fulvestrant in Women With Hormone Receptor Positive HER2 Negative Breast Cancer
NCT02107703 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE3
-
Adjuvant Palbociclib in Elderly Patients With Breast Cancer
NCT03609047 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Panitumumab, Nab-paclitaxel and Carboplatin for HER2 Negative Inflammatory Breast Cancer
NCT01036087 ·Status: COMPLETED ·Phase: PHASE2
-
Abemaciclib for Molecular Residual Disease Detected by Circulating Tumor DNA in HR+/HER2- Early Breast Cancer
NCT07292207 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2