A Three Day Trial of Azithromycin Plus Chloroquine for the Treatment of Uncomplicated Plasmodium Falciparum Malaria
NCT00282919 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 110
Last updated 2014-06-26
Summary
The treatment of symptomatic, uncomplicated malaria caused by P. falciparum in adults.
Conditions
- Falciparum Malaria
Interventions
- DRUG
-
Azithromycin plus chloroquine
dose of 2000 mg Azithromycin plus 600 mg chloroquine base
Sponsors & Collaborators
- lead INDUSTRY
Principal Investigators
-
Pfizer CT.gov Call Center · Pfizer
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2006-03-31
- Primary Completion
- 2008-02-29
- Completion
- 2008-02-29
Countries
- Colombia
- India
Study Locations
More Related Trials
-
Azithromycin Combination Therapy for Malaria
NCT00299208 ·Status: COMPLETED ·Phase: PHASE2
-
Azithromycin Plus Chloroquine Versus Artemether-Lumefantrine For The Treatment Of Uncomplicated P. Falciparum Malaria In Children In Africa
NCT00677833 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Azithromycin Plus Chloroquine Versus Mefloquine In the Treatment of Uncomplicated P. Falciparum Malaria.
NCT00367653 ·Status: COMPLETED ·Phase: PHASE3
-
Azithromycin Combination Therapy for the Treatment of Uncomplicated Falciparum Malaria in Bangladesh
NCT00356005 ·Status: COMPLETED ·Phase: PHASE2
-
Chloroquine (CQ) and Azithromycin (AZ) Combination for Malaria Prophylaxis
NCT03278808 ·Status: WITHDRAWN ·Phase: PHASE2
-
Evaluate Parasitological Clearance Rates And Pharmacokinetics Of The Combination Of Azithromycin And Chloroquine In Asymptomatic Pregnant Women With Falciparum Parasitemia In Africa
NCT01103713 ·Status: TERMINATED ·Phase: PHASE3
-
A Phase 1 Study To Estimate The Relative Bioavailability Of Fixed Combination Tablets Of Azithromycin And Chloroquine Compared To Co-Administered Individual Tablets Of Azithromycin And Chloroquine
NCT00844207 ·Status: COMPLETED ·Phase: PHASE1
-
Azithromycin Combination Therapy for the Treatment of Severe Malaria
NCT01374126 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase 1 Study To Estimate The Relative Bioavailability Of Co-Administered Formulations Of Azithromycin Microsphere And Chloroquine Test Formulation Compared With Co-Administered Immediate Release Individual Azithromycin And Chloroquine Tablets In Healthy Adult Subjects
NCT01100060 ·Status: COMPLETED ·Phase: PHASE1
-
Fosmidomycin and Azithromycin for Acute Uncomplicated Plasmodium Falciparum Malaria (P. Malaria) in Adults
NCT01464125 ·Status: UNKNOWN ·Phase: PHASE2
-
Efficacy, Tolerability, PK of OZ439 in Adults With Acute, Uncomplicated P.Falciparum or Vivax Malaria Mono-infection
NCT01213966 ·Status: COMPLETED ·Phase: PHASE2
-
OZ439 PhIIa Study in Plasmodium Falciparum: Extended Observation
NCT01713621 ·Status: COMPLETED ·Phase: PHASE2
-
Cotrifazid Safety and Efficacy Against Malaria
NCT00322907 ·Status: TERMINATED ·Phase: PHASE2
-
Effectiveness of OZ439 as a Gametocytocidal and Transmission Blocking Agent
NCT02431650 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Study to Characterise the Antimalarial and Transmission Blocking Activity of a Single Dose of DSM265 or OZ439 in Healthy Subjects With Induced Blood Stage Plasmodium Falciparum or Plasmodium Vivax Infection
NCT02573857 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Chloroquine Alone or in Combination for Malaria in Children in Malawi
NCT00379821 ·Status: COMPLETED ·Phase: PHASE3
-
Experimental Human Malaria Infection After Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine Prophylaxis
NCT01236612 ·Status: COMPLETED ·Phase: NA
-
Evaluate Azithromycin Plus Chloroquine And Sulfadoxine Plus Pyrimethamine Combinations For Intermittent Preventive Treatment Of Falciparum Malaria Infection In Pregnant Women In Africa
NCT01103063 ·Status: TERMINATED ·Phase: PHASE3
-
Efficacy of Chloroquine (CQ) Alone Compared to Concomitant CQ and Primaquine for Plasmodium Vivax Infection
NCT02691910 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
A Phase Ib Induced Malaria Infection Study With the Combination of OZ439 and DSM265
NCT02389348 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
A Pilot Study to Test Activity of Antimalarial Drugs Against an Induced Malaria Infection in Healthy Volunteers
NCT01055002 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
To Evaluate Current Efficacy of Antimalarials Used in Timika, Papua, Indonesia
NCT00157859 ·Status: COMPLETED ·Phase: NA
-
Efficacy and Safety of Sulphadoxine-pyrimethamine and Amodiaquine in Ghanaian Pregnant Women
NCT00131703 ·Status: COMPLETED ·Phase: PHASE3
-
Immunization With Plasmodium Falciparum Sporozoites Under Chloroquine or Chloroquine/Azithromycin Prophylaxis
NCT01783340 ·Status: WITHDRAWN ·Phase: PHASE1/PHASE2
-
Evaluation of Fosmidomycin and Clindamycin in the Treatment of Acute Uncomplicated Plasmodium Falciparum Malaria
NCT01361269 ·Status: UNKNOWN ·Phase: PHASE2