MedTrace Logo

The Effect of GLP-1 on Glucose Uptake in the Brain and Heart in Healthy Men

NCT00256256 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 10

Last updated 2007-10-30

No results posted yet for this study

Summary

Type 2 diabetes mellitus, T2D is a disease characterized by an immense growing prevalence world wide with an increased risk of myocardial infarction and stroke. GLP-1 has convincing effects on the high glucose levels in type 2 diabetic patients and is well tolerated. New animal studies indicate a protective effect of GLP-1 in the brain and the heart. The mechanism behind this is yet not known.

The study hypothesis is that GLP-1 will stimulate glucose-uptake in the brain and heart independent of insulin and thereby exert its protective effects.

Conditions

Interventions

DRUG

glucagon-like-peptide-1

Dose: 1.2pmol/kg/min for 6 hours

Sponsors & Collaborators

  • University of Aarhus

    lead OTHER

Principal Investigators

  • Ole Schmitz, MD,professor · Department of pharmacology, Aarhus university

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Model
CROSSOVER

Eligibility

Min Age
20 Years
Max Age
50 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2005-11-30
Completion
2007-01-31

Countries

  • Denmark

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00256256 on ClinicalTrials.gov