MedTrace Logo

Statin Therapy in Heart Failure: Potential Mechanisms of Benefit

NCT00233480 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 27

Last updated 2020-03-20

Study results available
· View outcomes & findings →

Summary

The goal of the investigators' study is to further understand the potentially beneficial effects of statin therapy in patients with heart failure. It is hypothesized that statins will 1) increase the heart's pumping ability 2) improve functioning of the sympathetic nervous system and 3) decrease immune activation in heart failure.

Conditions

  • Heart Failure, Congestive

Interventions

DRUG

atorvastatin

atorvastatin 10mg PO QD

DRUG

placebo

matched placebo Qd x 3 months

Sponsors & Collaborators

Principal Investigators

  • Tamara B Horwich, MD · UCLA Division of Cardiology

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
18 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2005-08-31
Primary Completion
2009-02-28
Completion
2009-02-28

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00233480 on ClinicalTrials.gov