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Estrogen for Treating Depression in Menopausal Women With Hot Flashes and Insomnia

NCT00227942 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL · Enrollment: 86

Last updated 2014-05-26

No results posted yet for this study

Summary

This study will evaluate the effectiveness of estrogen replacement therapy in treating depression in menopausal women with hot flashes and insomnia.

Conditions

  • Sleep Initiation and Maintenance Disorders
  • Depression

Interventions

DRUG

Estrogen Replacement Therapy

17-b-Estradiol Patch, .05 mg/day; applied for 7 days

DRUG

Zolpidem

10 mg/day, po qhs

DRUG

placebo

placebo

Sponsors & Collaborators

  • National Institute of Mental Health (NIMH)

    collaborator NIH

  • Hadine Joffe, MD

    lead OTHER

Principal Investigators

  • Hadine Joffe, MD, MSC · Massachusetts General Hospital

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Model
PARALLEL

Eligibility

Min Age
40 Years
Max Age
60 Years
Sex
FEMALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2003-08-31
Completion
2007-11-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00227942 on ClinicalTrials.gov