Intrinsic Optical Imaging Study to Map Neocortical Seizure in Human Epilepsy Patients
NCT00195052 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 34
Last updated 2025-06-24
Summary
The purpose of this study is to develop a technique for the intraoperative identification of human functional and epileptiform cortex using intrinsic signal imaging. The investigators propose that the ability to optically monitor neuronal activity in a large area of cortex in "real-time" will be a more sensitive and time-saving method than the electrical methods currently available. The applications of this technique will not only theoretically increase the safety and efficacy of many of neurosurgical procedures, but will be useful as an investigational tool to study human cortical physiology.
Conditions
Interventions
- DIAGNOSTIC_TEST
-
Intrinsic signal imaging of human cortex
Light is shined on the brain at 540 nm and 610 nm and images are acquired at 10 frames per second.
Sponsors & Collaborators
-
Weill Medical College of Cornell University
lead OTHER
Principal Investigators
-
Theodore H Schwartz, MD · Weill Cornell Medical College/New York Presbyterian Hospital
Eligibility
- Min Age
- 6 Years
- Max Age
- 65 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2002-05-31
- Primary Completion
- 2025-04-30
- Completion
- 2025-04-30
Countries
- United States
Study Locations
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