Intrinsic Optical Imaging Study to Map Neocortical Seizure in Human Epilepsy Patients

NCT00195052 · Status: TERMINATED · Type: OBSERVATIONAL · Enrollment: 34

Last updated 2025-06-24

No results posted yet for this study

Summary

The purpose of this study is to develop a technique for the intraoperative identification of human functional and epileptiform cortex using intrinsic signal imaging. The investigators propose that the ability to optically monitor neuronal activity in a large area of cortex in "real-time" will be a more sensitive and time-saving method than the electrical methods currently available. The applications of this technique will not only theoretically increase the safety and efficacy of many of neurosurgical procedures, but will be useful as an investigational tool to study human cortical physiology.

Conditions

Interventions

DIAGNOSTIC_TEST

Intrinsic signal imaging of human cortex

Light is shined on the brain at 540 nm and 610 nm and images are acquired at 10 frames per second.

Sponsors & Collaborators

  • Weill Medical College of Cornell University

    lead OTHER

Principal Investigators

  • Theodore H Schwartz, MD · Weill Cornell Medical College/New York Presbyterian Hospital

Eligibility

Min Age
6 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2002-05-31
Primary Completion
2025-04-30
Completion
2025-04-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00195052 on ClinicalTrials.gov