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Biomarkers of iNOS Activity in COPD, Asthma, Healthy Control

NCT00159302 · Status: WITHDRAWN · Type: OBSERVATIONAL

Last updated 2019-07-10

No results posted yet for this study

Summary

This pilot study will measure the baseline levels and the intra- and inter-subject variability of exhaled (alveolar and bronchial) and nasal NO in smoking subjects with mild and moderate COPD on or off steroid treatment, smoking healthy volunteers and non-smoking mild asthmatics off steroids, using multiple exhalation flow rates.

I

Conditions

  • Healthy Smokers
  • Healthy Non-smokers
  • Patients With Mild Asthma
  • Patints With COPD (GOLD II)

Interventions

PROCEDURE

Induced Sputum

PROCEDURE

Exhaled Nitric Oxide

PROCEDURE

Nasal Nitric Oxide

PROCEDURE

Blood Tests

PROCEDURE

24hr Urine Samples

PROCEDURE

Exhaled Breath Condensate

PROCEDURE

Spirometry

Sponsors & Collaborators

Principal Investigators

  • Sergei A Kharitonov, MD PhD · Imperial College London

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2003-09-30
Primary Completion
2006-09-30
Completion
2006-09-30

Countries

  • United Kingdom

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00159302 on ClinicalTrials.gov