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Impact of Exercise Training on Exercise Capacity in Patients With Severe Chronic Heart Failure

NCT00176384 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2007-08-01

No results posted yet for this study

Summary

Patients with heart failure are limited in their exercise capacity due to skeletal muscle alteration and an impairment of peripheral perfusion. Regular physical exercise training has been shown to partially correct these peripheral maladaptations in patients with stable heart failure, which was associated with an improvement in exercise capacity. However, it is unknown so far, whether regular physical activity also exerts beneficial effects in patients with severe chronic heart failure.

Aim of the trial is therefore to assess the effects of aerobic exercise training on exercise capacity, muscle maladaptations and peripheral perfusion in patients with severe chronic heart failure according to NYHA class III b.

Conditions

Interventions

BEHAVIORAL

Aerobic endurance exercise training (ergometer)

Sponsors & Collaborators

  • Deutsche Stiftung für Herzforschung

    collaborator OTHER

  • University of Leipzig

    lead OTHER

Principal Investigators

  • Rainer P Hambrecht, MD · University of Leipzig, Heart Center, Department of Internal Medicine / Cardiology, Leipzig, Germany

Study Design

Allocation
RANDOMIZED
Masking
NONE
Model
SINGLE_GROUP

Eligibility

Min Age
18 Years
Max Age
75 Years
Sex
MALE
Healthy Volunteers
No

Timeline & Regulatory

Start
2003-03-31
Completion
2006-12-31

Countries

  • Germany

Study Locations

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Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00176384 on ClinicalTrials.gov