The Role of NK Cells to Detect Blood Infection in ALL.
NCT06160115 · Status: NOT_YET_RECRUITING · Type: OBSERVATIONAL · Enrollment: 56
Last updated 2023-12-07
Summary
1. Assess possibility of prediction of blood stream infections in ALL patients by profiling of NK cells using flow cytometry.
2. Assess the role of NK cells in development of drug resistance post chemotherapy.
Conditions
- Acute Lymphoblastic Leukemia
- Bloodstream Infection
Interventions
- DEVICE
-
Flow cytometry
1. Profiling of NK cells using flow cytometry on peripheral blood and bone marrow aspirate samples. 2. Isolation and identification of pathogens causing BSI and bacterial drug susceptibility testing using VITEK compact fully automatic microbial identification instrument.
Sponsors & Collaborators
-
Assiut University
lead OTHER
Principal Investigators
-
Shaimaa G Mansour, Professor · South Egypt Cancer Institure, Assiut, Egypt
-
Eman M Abdel Rahman, Lecturer · Assiut University
Eligibility
- Min Age
- 0 Years
- Max Age
- 17 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2024-02-01
- Primary Completion
- 2025-02-01
- Completion
- 2025-04-01
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