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Contraction (Exercise) Mediated Glucose Uptake as a Therapeutic Target in Type 2 Diabetes

NCT00168519 · Status: COMPLETED · Phase: NA · Type: INTERVENTIONAL · Enrollment: 40

Last updated 2009-12-15

No results posted yet for this study

Summary

The purpose of this project is to determine whether glucose metabolism can be improved by administering a substance (nitric oxide donor) normally released by muscles during exercise.

Conditions

  • Diabetes Mellitus, Type 2

Interventions

DRUG

nitroprusside, pentalong, imdur, AICAR, isoptin

Sodium Nitroprusside - one 30 minute intravenous infusion Pentalong - two tablets orally (total 160mg) Imdur - two tablets orally (total 120mg)

Sponsors & Collaborators

  • National Health and Medical Research Council, Australia

    collaborator OTHER

  • Hoffmann-La Roche

    collaborator INDUSTRY

  • Life for a Child Program, Diabetes Australia

    collaborator OTHER

  • Baker Heart Research Institute

    lead OTHER

Principal Investigators

  • Bronwyn A Kingwell, PhD · Baker Heart Research Institute

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Model
CROSSOVER

Eligibility

Min Age
18 Years
Max Age
65 Years
Sex
MALE
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2002-10-31
Completion
2009-04-30

Countries

  • Australia

Study Locations

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Entities

Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00168519 on ClinicalTrials.gov