Rosuvastatin Affecting Aortic Valve Endothelium
NCT00114491 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 200
Last updated 2006-10-31
Summary
Recent studies support the hypothesis that aortic stenosis (AS) develops due to atherosclerosis affecting the aortic valve endothelium. The study's aim was to assess Rosuvastatin on the hemodynamic progression and inflammatory markers of AS by treating low-density lipoprotein (LDL) in patients with AS according to the National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATPIII) guidelines for one year.
Conditions
Interventions
- DRUG
-
Rosuvastatin
Sponsors & Collaborators
- collaborator OTHER
-
Hospital Pedro Hispano
lead OTHER
Principal Investigators
-
Luis M Moura · Hospital Pedro Hispano
Eligibility
- Min Age
- 50 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 2003-09-30
- Completion
- 2005-05-31
Countries
- Portugal
Study Locations
More Related Trials
-
Impact of Rosuvastatin on Endothelial Function and Inflammation in Patients With Chronic Heart Failure
NCT00176332 ·Status: COMPLETED ·Phase: PHASE2
-
Rosuvastatin Effect on Serial Echocardiographic Measurement of Coronary Flow Velocity Reserve
NCT01490398 ·Status: COMPLETED ·Phase: PHASE4
-
Evaluation of the Efficacy of Rosuvastatin in Daily Practice (TARGET)
NCT00396110 ·Status: COMPLETED
-
A Study To Evaluate the Effect of Rosuvastatin On Intravascular Ultrasound-Derived Coronary Atheroma Burden (ASTEROID)
NCT00240318 ·Status: COMPLETED ·Phase: PHASE3
-
A Trial to Evaluate the Effect of Rosuvastatin on Inflammation in Patients Undergoing Isolated Cardiac Valve Surgery
NCT01425398 ·Status: COMPLETED ·Phase: PHASE3
-
Study of PF-04965842 Effect on Rosuvastatin Pharmacokinetics in Healthy Participants
NCT03806101 ·Status: COMPLETED ·Phase: PHASE1
-
Multicenter, Prospective, Randomized, Controlled, Double-blind Trial on the Impact of Rosuvastatin on Subclinical Markers of Atherosclerosis in Patients With Primary Necrotizing Vasculitides
NCT02117453 ·Status: COMPLETED ·Phase: PHASE3
-
Assessment of the Lipid Lowering Effect of Rosuvastatin Compared to Atorvastatin in Subjects With Coronary Heart Disease
NCT00235950 ·Status: COMPLETED ·Phase: PHASE4
-
Rosuvastatin and Ischemia Reperfusion
NCT00315510 ·Status: COMPLETED ·Phase: PHASE2
-
Effect of Rosuvastatin on Left Ventricular Remodeling
NCT00505154 ·Status: COMPLETED ·Phase: PHASE3
-
Dose-dependent Effect of Rosuvastatin on Long-term Clinical Outcomes After PCI
NCT02859480 ·Status: UNKNOWN ·Phase: PHASE4
-
Registry On Efficacy and Safety Of Rosuvastatin, and Atorvastatin and Simvastatin In Hypercholesterolaemia
NCT01352897 ·Status: COMPLETED
-
The Effect of Rosuvastatin on Adenosine Metabolism
NCT00554138 ·Status: COMPLETED ·Phase: NA
-
Evaluation of the Efficacy of Rosuvastatin in Daily Practice in Untreated High Risk Patients (CHALLENGE)
NCT00574782 ·Status: COMPLETED
-
Statin Contrast Induced Nephropathy Prevention
NCT01185938 ·Status: COMPLETED ·Phase: PHASE4
-
Rosuvastatin and Evolocumab for Coronary Artery Disease
NCT05984953 ·Status: COMPLETED
-
Depression and Cardiovascular Risk Markers: Effects of Rosuvastatin Therapy
NCT00951132 ·Status: WITHDRAWN ·Phase: PHASE2
-
Is Augmentation of PORH by Rosuvastatin Adenosine-receptor Mediated?
NCT00851175 ·Status: COMPLETED ·Phase: PHASE4
-
A Study to Evaluate the Efficacy and Safety of Rosuvastatin in the Treatment of the Carotid Atherosclerotic Plaques
NCT02532309 ·Status: UNKNOWN ·Phase: PHASE4
-
A Study to Investigate the Effect of Oral Ticagrelor on the Pharmacokinetics of Oral Rosuvastatin When Given in Healthy Participants
NCT06554821 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Intensive Lipid Lowering Treatment Compared to Moderate Lipid Lowering Treatment on Carotid Intima-media Thickness (CIMT)
NCT01203982 ·Status: COMPLETED ·Phase: PHASE4
-
Effect of Rosuvastatin Therapy on HDL2 Level
NCT02593487 ·Status: UNKNOWN ·Phase: PHASE4
-
Rho Kinase in Patients With Atherosclerosis
NCT00115830 ·Status: COMPLETED ·Phase: PHASE3
-
Effect of Rosuvastatin on Systemic Sclerosis-related Pulmonary Hypertension
NCT00984932 ·Status: COMPLETED ·Phase: PHASE3
-
Different Doses of Rosuvastatin Therapy on Regression of Critical Coronary Atherosclerosis in ACS Patients
NCT02420899 ·Status: UNKNOWN ·Phase: NA