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Antidepressant Medication Treatment for Depression in Individuals With Chronic Heart Failure

NCT00078286 · Status: COMPLETED · Phase: PHASE2/PHASE3 · Type: INTERVENTIONAL · Enrollment: 469

Last updated 2013-02-27

Study results available
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Summary

This study will examine the effect of antidepressant medication on rates of death and disease in depressed people with chronic heart failure.

Conditions

Interventions

DRUG

Sertraline

Dosage ranging from 50 mg to 200 mg once a day

DRUG

Placebo

Dosage ranging from 50 mg to 200 mg once a day

Sponsors & Collaborators

  • National Institute of Mental Health (NIMH)

    collaborator NIH

  • Duke University

    lead OTHER

Principal Investigators

  • Ranga Krishnan, PhD · Duke University

Study Design

Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
QUADRUPLE
Model
PARALLEL

Eligibility

Min Age
45 Years
Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2003-11-30
Primary Completion
2008-03-31
Completion
2008-09-30

Countries

  • United States

Study Locations

More Related Trials

Entities

Drugs
Diseases
Companies

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT00078286 on ClinicalTrials.gov