Proteomic Profiling in Diagnosing Non-Small Cell Lung Cancer in Patients Who Are Undergoing Lung Resection for Suspicious Stage I Lung Lesions
NCT00077324 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 1000
Last updated 2016-07-06
Summary
RATIONALE: Evaluating specific proteins in the blood may be an effective and noninvasive procedure to help doctors determine if a patient has early non-small cell lung cancer.
PURPOSE: This clinical trial is studying proteomic profiling to see how well it works in diagnosing non-small cell lung cancer in patients who are undergoing resection for suspicious (abnormal) stage I lung lesions.
Conditions
Interventions
- GENETIC
-
proteomic profiling
- OTHER
-
surface-enhanced laser desorption/ionization-time of flight mass spectrometry
- PROCEDURE
-
biopsy
- PROCEDURE
-
surgery
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Alliance for Clinical Trials in Oncology
lead OTHER
Principal Investigators
-
David H. Harpole, MD · Duke Cancer Institute
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2004-02-29
- Primary Completion
- 2011-11-30
- Completion
- 2011-11-30
Countries
- United States
- Canada
Study Locations
More Related Trials
-
Study of Proteins in Tumor Samples From Patients With Non-Small Cell Lung Cancer
NCT01415739 ·Status: WITHDRAWN
-
Plasma Proteomic Biomarkers for Early Diagnosis of Lung Cancer
NCT05742204 ·Status: ACTIVE_NOT_RECRUITING
-
Study of Tissue Samples From Patients With Non-Small Cell Lung Cancer
NCT01414595 ·Status: COMPLETED
-
A Multi-Center Trial of the ProLung Test™
NCT01566682 ·Status: COMPLETED
-
Surgical Versus Non-surgical Staging of Lung Cancer
NCT01117714 ·Status: TERMINATED ·Phase: NA
-
S0424 - Carcinogens in Lung Tissue From Smokers (Closed to Entry as of 7/15/07) and Non-Smokers With Newly Diagnosed Stage I, Stage II, or Stage III Non-Small Cell Lung Cancer
NCT00450281 ·Status: COMPLETED
-
Clinical Validation of Freenome Multiomics Blood Test for Lung Cancer Screening
NCT06122077 ·Status: RECRUITING
-
Fluid Biopsy for the Diagnosis of Lung Cancer
NCT04162678 ·Status: TERMINATED
-
Detection of Genetic Markers of Lung Cancer
NCT00280202 ·Status: RECRUITING
-
Respiratory Muscle Training Before Surgery in Preventing Lung Complications in Patients With Stage I-IIIB Lung Cancer
NCT04067830 ·Status: RECRUITING ·Phase: PHASE2
-
The Utility of Circulating Tumor Cells as Confirmation of Pathologic Diagnosis in Patients With Suspected Early Stage Non-small Cell Lung Cancer
NCT02380196 ·Status: COMPLETED
-
Biomarkers in Tissue and Blood Samples From Patients With Early-Stage Non-Small Cell Lung Cancer
NCT01139944 ·Status: COMPLETED
-
Studying Tumor Tissue Samples From Patients With Early-Stage Non-Small Cell Lung Cancer
NCT01517971 ·Status: COMPLETED
-
Collection of Blood Samples in Patients With Non-small Cell Lung Cancer
NCT03492801 ·Status: TERMINATED
-
PROspective Trial on EOsinophilia in Non-Small Cell Lung Cancer (NSCLC).
NCT05602259 ·Status: RECRUITING ·Phase: NA
-
Feasibility of Targeted Bronchial Washing for Molecular Testing by Next Generation Sequencing in Early-stage Lung Cancer
NCT06301295 ·Status: ACTIVE_NOT_RECRUITING ·Phase: NA
-
Saliva mRNA Expression Profiling for Early Stage Non-Small Cell Lung Cancer Screening
NCT00607425 ·Status: TERMINATED
-
Identifying Biomarkers for Lung Cancer Using Tissue Samples From Patients With Lung Cancer and From Healthy Participants
NCT00899028 ·Status: COMPLETED
-
Detection of Early Lung Cancer by Serum Protein Expression Profiling
NCT00175578 ·Status: UNKNOWN
-
Feasibility of Bronchial Washing Fluid for Molecular Testing With Next Generation Sequencing in Lung Cancer
NCT06141005 ·Status: COMPLETED ·Phase: NA
-
Lung Tumor Protein Synthesis Rates in Lung Cancer Patients
NCT05794529 ·Status: RECRUITING
-
Early Diagnosis of Pulmonary Nodules
NCT01752114 ·Status: COMPLETED
-
Testing Tumor Tissue and Blood to Help Select Personalized Treatments for Patients With Suspected Lung Cancers
NCT04712877 ·Status: RECRUITING
-
A Randomized Controlled Trial Evaluating the Effectiveness of a Novel Risk-Stratified Screening Strategy for Lung Cancer
NCT07078032 ·Status: NOT_YET_RECRUITING ·Phase: NA
-
Feasibility of Cell-Free DNA Liquid Biopsy in Screening High-Risk Patients for Lung Cancer
NCT05384769 ·Status: RECRUITING ·Phase: NA