Methotrexate, Procarbazine, Lomustine, Dexamethasone, and Cytarabine in Treating Patients With Primary CNS Lymphoma
NCT00074191 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 1
Last updated 2017-04-21
Summary
RATIONALE: Drugs used in chemotherapy, such as methotrexate, procarbazine, lomustine, dexamethasone, and cytarabine, use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy in treating patients who have primary CNS lymphoma.
Conditions
Interventions
- DRUG
- DRUG
- DRUG
-
lomustine
- DRUG
-
methotrexate
- DRUG
-
procarbazine hydrochloride
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
OHSU Knight Cancer Institute
lead OTHER
Principal Investigators
-
Edward A. Neuwelt, MD · OHSU Knight Cancer Institute
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
Eligibility
- Min Age
- 16 Years
- Max Age
- 75 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2000-01-31
- Primary Completion
- 2000-10-31
- Completion
- 2000-10-31
Countries
- United States
Study Locations
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