Carboxyamidotriazole and Paclitaxel in Treating Patients With Advanced Solid Tumors or Refractory Lymphomas
NCT00019019 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 70
Last updated 2012-03-15
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
PURPOSE: This phase I trial is studying the side effects and best dose of carboxyamidotriazole and paclitaxel in treating patients with advanced solid tumors or refractory lymphomas.
Conditions
- Brain and Central Nervous System Tumors
- Breast Cancer
- Kidney Cancer
- Lung Cancer
- Lymphoma
- Melanoma (Skin)
- Ovarian Cancer
- Small Intestine Cancer
- Unspecified Adult Solid Tumor, Protocol Specific
Interventions
- DRUG
-
carboxyamidotriazole
- DRUG
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
National Institutes of Health Clinical Center (CC)
lead NIH
Principal Investigators
-
Virginia Kwitkowski, MS, RN, CS, CRNP · National Cancer Institute (NCI)
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1994-10-31
- Primary Completion
- 2006-07-31
- Completion
- 2006-07-31
Countries
- United States
Study Locations
More Related Trials
-
Cyclophosphamide Plus Topotecan in Treating Patients With Refractory or Relapsed Acute Myelogenous Leukemia
NCT00003340 ·Status: COMPLETED ·Phase: PHASE2
-
Copanlisib Hydrochloride and Nivolumab in Treating Patients With Recurrent or Refractory Diffuse Large B-cell Lymphoma or Primary Mediastinal Large B-cell Lymphoma
NCT03484819 ·Status: COMPLETED ·Phase: PHASE2
-
Carfilzomib in Treating Patients With Relapsed or Refractory T-Cell Lymphoma
NCT01336920 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy in Treating Patients With Relapsed or Refractory Intermediate-Grade or High-Grade Non-Hodgkin's Lymphoma
NCT00006125 ·Status: COMPLETED ·Phase: PHASE2
-
Nivolumab and Combination Chemotherapy in Treating Participants With Diffuse Large B-Cell Lymphoma
NCT03704714 ·Status: SUSPENDED ·Phase: PHASE1/PHASE2
-
Phase I Master Protocol of Novel Combination Therapy for Patients With Relapsed or Refractory Aggressive B-Cell Lymphoma
NCT04161248 ·Status: ACTIVE_NOT_RECRUITING ·Phase: EARLY_PHASE1
-
Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma or Acute Lymphocytic Leukemia
NCT00005977 ·Status: COMPLETED ·Phase: PHASE3
-
Talabostat and Pembrolizumab for the Treatment of Advanced Solid Cancers
NCT04171219 ·Status: TERMINATED ·Phase: PHASE2
-
Combination Chemotherapy With or Without Bortezomib in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma
NCT00513955 ·Status: COMPLETED ·Phase: PHASE2
-
Axatilimab in Combination With Retifanlimab and Paclitaxel for the Treatment of Patients With Advanced or Metastatic Solid Tumors
NCT06320405 ·Status: RECRUITING ·Phase: PHASE1/PHASE2
-
Combination Chemotherapy and Rituximab in Treating Patients With Diffuse Large B-Cell Non-Hodgkin Lymphoma
NCT00974792 ·Status: UNKNOWN ·Phase: PHASE2
-
Decitabine in Treating Patients With Advanced Refractory Solid Tumors or Lymphomas
NCT00089089 ·Status: TERMINATED ·Phase: PHASE1
-
Venetoclax and Vincristine in Treating Patients With Relapsed or Refractory T-cell or B-cell Acute Lymphoblastic Leukemia
NCT03504644 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1/PHASE2
-
Evaluation of the Combination of Romidepsin and Carfilzomib in Relapsed/Refractory Peripheral T Cell Lymphoma Patients
NCT03141203 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
CCI-779 in Treating Patients With Recurrent or Refractory B-Cell Non-Hodgkin's Lymphoma or Chronic Lymphocytic Leukemia
NCT00290472 ·Status: COMPLETED ·Phase: PHASE2
-
Phase 1 Clinical Trial of NPI-0052 in Patients With Advanced Solid Tumor Malignancies or Refractory Lymphoma
NCT00396864 ·Status: COMPLETED ·Phase: PHASE1
-
Combination Chemotherapy in Treating Patients With Advanced Hodgkin's Lymphoma
NCT00002715 ·Status: COMPLETED ·Phase: PHASE2
-
Ibrutinib and Palbociclib in Treating Patients With Previously Treated Mantle Cell Lymphoma
NCT02159755 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE1
-
Combination Chemotherapy in Treating Patients With Relapsed or Refractory Aggressive Non-Hodgkin's Lymphoma
NCT00053105 ·Status: UNKNOWN ·Phase: PHASE1
-
Methotrexate, Procarbazine, Lomustine, Dexamethasone, and Cytarabine in Treating Patients With Primary CNS Lymphoma
NCT00074191 ·Status: COMPLETED ·Phase: PHASE2
-
Avelumab, Utomilumab, Rituximab, Ibrutinib, and Combination Chemotherapy in Treating Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma or Mantle Cell Lymphoma
NCT03440567 ·Status: COMPLETED ·Phase: PHASE1
-
Genetically Engineered Cells (Anti-CD19/CD20/CD22 CAR T-cells) for the Treatment of Relapsed or Refractory Lymphoid Malignancies
NCT05418088 ·Status: RECRUITING ·Phase: PHASE1
-
Testing a New Anti-cancer Drug Combination, Entinostat and GSK525762C, for Advanced and Refractory Solid Tumors and Lymphomas
NCT03925428 ·Status: WITHDRAWN ·Phase: PHASE1
-
A Study of Ruxolitinib and Duvelisib in People With Lymphoma
NCT05010005 ·Status: RECRUITING ·Phase: PHASE1
-
Combination Chemotherapy Plus Rituximab in Treating Patients With Recurrent or Refractory Non-Hodgkin's Lymphoma
NCT00007865 ·Status: COMPLETED ·Phase: PHASE2