Irinotecan in Treating Patients With Refractory Solid Tumors and Liver Dysfunction
NCT00037804 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL
Last updated 2009-08-14
Summary
Drugs used in chemotherapy us different ways to stop tumor cells from dividing so they stop growing or die. Irinotecan may be effective in treating patients with refractory solid tumors and liver dysfunction.
Conditions
- Unspecified Adult Solid Tumor
- Chemotherapy
- Liver Dysfunction
- Neoplasms, Solid Tumor
Interventions
- DRUG
Sponsors & Collaborators
- lead INDUSTRY
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
Countries
- United States
Study Locations
More Related Trials
-
Irinotecan in Treating Patients With Advanced Gallbladder or Bile Duct Cancer
NCT00003276 ·Status: COMPLETED ·Phase: PHASE2
-
Phase I and Pharmacokinetic Study of Biweekly PEP02 in mCRC Refractory to 1st-line Oxaliplatin Base Therapy
NCT00940758 ·Status: COMPLETED ·Phase: PHASE1
-
Capecitabine and Irinotecan in Treating Patients With Locally Advanced, Recurrent, or Metastatic Colorectal Cancer
NCT00022698 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan-Eluting Beads in Treating Patients With Refractory Metastatic Colon or Rectal Cancer That Has Spread to the Liver
NCT02110953 ·Status: TERMINATED ·Phase: PHASE1
-
NKTR-102 Versus Irinotecan in Patients With Second-Line, Irinotecan-Naïve, KRAS Mutant, Colorectal Cancer
NCT00856375 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan in Treating Patients With Metastatic Colorectal Cancer
NCT00003544 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Safety and Efficacy of Ribociclib and Trametinib in Patients With Metastatic or Advanced Solid Tumors
NCT02703571 ·Status: TERMINATED ·Phase: PHASE1
-
A Phase II Multicenter, Randomized, Placebo Controlled, Double Blinded Clinical Study of KD018 as a Modulator of Irinotecan Chemotherapy in Patients With Metastatic Colorectal Cancer
NCT00730158 ·Status: COMPLETED ·Phase: PHASE2
-
Phase Ib/II Trial of Nal-Irinotecan and Nivolumab as Second-Line Treatment in Patients With Advanced Biliary Tract Cancer
NCT03785873 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Injection of IP-001 Into Thermally Ablated Hepatic Tumors in Patients With Colorectal Liver Metastases
NCT07321847 ·Status: NOT_YET_RECRUITING ·Phase: PHASE2/PHASE3
-
SU5416 and Irinotecan in Treating Patients With Advanced Colorectal Cancer
NCT00005818 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Irinotecan in Treating Patients With Colorectal Cancer
NCT00003843 ·Status: TERMINATED
-
Irinotecan Plus Raltitrexed as Second-line Treatment in Advanced Colorectal Cancer Patients
NCT03053167 ·Status: UNKNOWN ·Phase: PHASE2
-
Evaluate the Efficacy of Irinotecan Versus Oxaliplatin in the First-line Treatment of Refractory Metastatic Colorectal Cancer
NCT03567629 ·Status: UNKNOWN ·Phase: PHASE2
-
IRX-2 Regimen Combined With Nivolumab in Recurrent/Metastatic Solid Tumors
NCT03758781 ·Status: COMPLETED ·Phase: PHASE1
-
Study of Irinotecan Plus Capecitabine to Treat Advanced Colorectal Cancer
NCT01322152 ·Status: COMPLETED ·Phase: PHASE2
-
Testing Olaparib and AZD6738 in IDH1 and IDH2 Mutant Tumors
NCT03878095 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
Irinotecan and Cediranib in Treating Patients With Metastatic Colorectal Cancer That Did Not Respond to Previous Oxaliplatin, Fluoropyrimidine, and Bevacizumab
NCT00588900 ·Status: TERMINATED ·Phase: PHASE2
-
A Phase 2 Trial of Regorafenib as A Single Agent in Advanced and Metastatic Biliary Tract Carcinoma/Cholangiocarcinoma Patients Who Have Failed First-line Chemotherapy
NCT02053376 ·Status: COMPLETED ·Phase: PHASE2
-
For Prevention of Diarrhea in Patients Diagnosed With Metastatic Colorectal Cancer Treated With Chemotherapy
NCT00037180 ·Status: TERMINATED ·Phase: PHASE2
-
Irinotecan and Cetuximab for Colorectal Cancer as Second Line Therapy
NCT00336856 ·Status: COMPLETED ·Phase: PHASE2
-
ISIS 2503 in Treating Patients With Metastatic and/or Locally Recurrent Colorectal Cancer
NCT00004193 ·Status: TERMINATED ·Phase: PHASE2
-
S1406 Phase II Study of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF Mutant Metastatic Colorectal Cancer
NCT02164916 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan and Alisertib in Treating Patients With Advanced Solid Tumors or Colorectal Cancer
NCT01923337 ·Status: COMPLETED ·Phase: PHASE1
-
Phase I/II Study of KRN330 Plus Irinotecan in Patients With Metastatic Colorectal Cancer
NCT00838578 ·Status: TERMINATED ·Phase: PHASE1/PHASE2