Irinotecan in Treating Patients With Metastatic Colorectal Cancer
NCT00003544 · Status: COMPLETED · Phase: PHASE2 · Type: INTERVENTIONAL
Last updated 2013-06-26
Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.
PURPOSE: Phase II trial to study the effectiveness of irinotecan in treating patients with metastatic colorectal cancer.
Conditions
Interventions
- DRUG
-
irinotecan hydrochloride
- PROCEDURE
-
surgical procedure
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
Memorial Sloan Kettering Cancer Center
lead OTHER
Principal Investigators
-
Leonard B. Saltz, MD · Memorial Sloan Kettering Cancer Center
Study Design
- Purpose
- TREATMENT
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1998-06-30
- Primary Completion
- 2001-03-31
- Completion
- 2001-03-31
Countries
- United States
Study Locations
More Related Trials
-
Radiation Therapy Plus Irinotecan in Treating Patients With Colon Cancer
NCT00003344 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Study of Irinotecan Plus Capecitabine to Treat Advanced Colorectal Cancer
NCT01322152 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan and Celecoxib in Treating Patients With Unresectable or Metastatic Colorectal Cancer
NCT00084721 ·Status: COMPLETED ·Phase: PHASE1
-
Monoclonal Antibody Plus Chemotherapy in Treating Patients With Advanced Colorectal Cancer That Overexpresses HER2
NCT00003995 ·Status: COMPLETED ·Phase: PHASE2
-
Celecoxib, Capecitabine, and Irinotecan in Treating Patients With Recurrent or Metastatic Colorectal Cancer
NCT00258232 ·Status: COMPLETED ·Phase: PHASE2
-
Phase I/Randomized Phase II Study of Second Line Therapy With Irinotecan + Cetuximab +/- RAD001 for Colorectal Cancer
NCT00522665 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Irinotecan With or Without Oxaliplatin in Treating Patients With Metastatic Colorectal Cancer
NCT00012389 ·Status: COMPLETED ·Phase: PHASE3
-
Safety, Tolerability and Pharmacokinetics of Oral Tablet of Irinotecan in Adult Patients With Solid Tumors
NCT03295084 ·Status: COMPLETED ·Phase: PHASE1
-
NKTR-102 Versus Irinotecan in Patients With Second-Line, Irinotecan-Naïve, KRAS Mutant, Colorectal Cancer
NCT00856375 ·Status: COMPLETED ·Phase: PHASE2
-
Utomilumab, Cetuximab, and Irinotecan Hydrochloride in Treating Patients With Metastatic Colorectal Cancer
NCT03290937 ·Status: COMPLETED ·Phase: PHASE1
-
Monoclonal Antibody Therapy Plus Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer
NCT00003543 ·Status: COMPLETED ·Phase: PHASE1
-
S9923 R115777 in Treating Patients With Advanced Colorectal Cancer
NCT00005833 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Irinotecan and AZD1775, a Selective Wee 1 Inhibitor, in RAS or BRAF Mutated, Second-line Metastatic Colorectal Cancer
NCT02906059 ·Status: COMPLETED ·Phase: PHASE1
-
Savolitinib in Treating Patients With MET Amplified Metastatic or Unresectable Colorectal Cancer
NCT03592641 ·Status: TERMINATED ·Phase: PHASE2
-
Ro 31-7453 in Treating Patients With Recurrent or Refractory Metastatic Colorectal Cancer
NCT00016250 ·Status: COMPLETED ·Phase: PHASE2
-
Phase II Study to Evaluate G17DT in Combination With Irinotecan in Patients With Colorectal Carcinoma
NCT02118064 ·Status: COMPLETED ·Phase: PHASE2
-
Study of Irinotecan & Capecitabine in Metastatic Colorectal Cancer
NCT00506168 ·Status: TERMINATED ·Phase: PHASE2
-
Irinotecan and Cediranib in Treating Patients With Metastatic Colorectal Cancer That Did Not Respond to Previous Oxaliplatin, Fluoropyrimidine, and Bevacizumab
NCT00588900 ·Status: TERMINATED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Patients With Advanced or Metastatic Colorectal Cancer
NCT00030797 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan With or Without Capecitabine as Second-Line Therapy in Treating Older Patients With Progressive, Metastatic Colorectal Cancer That Cannot Be Removed By Surgery
NCT00303745 ·Status: UNKNOWN ·Phase: PHASE2
-
Tocladesine in Treating Patients With Recurrent or Progressive Metastatic Colorectal Cancer
NCT00021268 ·Status: UNKNOWN ·Phase: PHASE1
-
Irinotecan and Cetuximab for Colorectal Cancer as Second Line Therapy
NCT00336856 ·Status: COMPLETED ·Phase: PHASE2
-
Erlotinib in Treating Patients With Recurrent or Metastatic Colorectal Cancer
NCT00032110 ·Status: COMPLETED ·Phase: PHASE2
-
Pertuzumab and Cetuximab in Treating Patients With Previously Treated Locally Advanced or Metastatic Colorectal Cancer
NCT00551421 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
SB-715992 in Treating Patients With Advanced or Metastatic Colorectal Cancer
NCT00103311 ·Status: COMPLETED ·Phase: PHASE2