ISIS 2503 in Treating Patients With Metastatic and/or Locally Recurrent Colorectal Cancer
NCT00004193 · Status: TERMINATED · Phase: PHASE2 · Type: INTERVENTIONAL · Enrollment: 25
Last updated 2013-04-12
Summary
RATIONALE: ISIS 2503 may kill cancer cells by inhibiting a gene that promotes the development and growth of cancer.
PURPOSE: Phase II trial to study the effectiveness of ISIS 2503 in treating patients who have metastatic and/or locally recurrent colorectal cancer.
Conditions
Interventions
- DRUG
-
ISIS 2503
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
University of Alabama at Birmingham
lead OTHER
Principal Investigators
-
Mansoor N. Saleh, MD · University of Alabama at Birmingham
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- SINGLE_GROUP
Eligibility
- Min Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 1999-01-31
- Primary Completion
- 2000-11-30
- Completion
- 2000-11-30
Countries
- United States
Study Locations
More Related Trials
-
Chemokine-Modulatory Regimen for Recurrent Resectable Colorectal Cancer
NCT01545141 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Erlotinib in Treating Patients With Recurrent or Metastatic Colorectal Cancer
NCT00032110 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan in Treating Patients With Metastatic or Recurrent Colorectal Cancer
NCT00002933 ·Status: COMPLETED ·Phase: PHASE2
-
Celecoxib, Capecitabine, and Irinotecan in Treating Patients With Recurrent or Metastatic Colorectal Cancer
NCT00258232 ·Status: COMPLETED ·Phase: PHASE2
-
AZD0530 (NSC 735464) in Treating Patients With Previously Treated Metastatic Colon Cancer or Rectal Cancer
NCT00397878 ·Status: TERMINATED ·Phase: PHASE2
-
Irofulven in Treating Patients With Metastatic or Recurrent Colorectal Cancer
NCT00003786 ·Status: WITHDRAWN ·Phase: PHASE2
-
Study of Tumor Tissue Testing in Selecting Treatment for Patients With Metastatic or Locally Advanced Colorectal Cancer
NCT00975897 ·Status: COMPLETED ·Phase: PHASE2/PHASE3
-
Capecitabine and Irinotecan in Treating Patients With Locally Advanced, Recurrent, or Metastatic Colorectal Cancer
NCT00022698 ·Status: COMPLETED ·Phase: PHASE2
-
S9923 R115777 in Treating Patients With Advanced Colorectal Cancer
NCT00005833 ·Status: COMPLETED ·Phase: PHASE2
-
Tocladesine in Treating Patients With Recurrent or Progressive Metastatic Colorectal Cancer
NCT00021268 ·Status: UNKNOWN ·Phase: PHASE1
-
Azacitidine and Entinostat in Treating Patients With Metastatic Colorectal Cancer
NCT01105377 ·Status: COMPLETED ·Phase: PHASE2
-
Irinotecan and Celecoxib in Treating Patients With Unresectable or Metastatic Colorectal Cancer
NCT00084721 ·Status: COMPLETED ·Phase: PHASE1
-
Study of TAS-102 in Patients With Metastatic Colorectal Cancer Refractory to Standard Chemotherapies
NCT01607957 ·Status: COMPLETED ·Phase: PHASE3
-
Study of Hepatic Arterial Infusion With Intravenous Irinotecan, 5FU and Leucovorin With or Without Panitumumab, in Patients With Wild Type RAS Who Have Resected Hepatic Metastases From Colorectal Cancer
NCT01312857 ·Status: COMPLETED ·Phase: PHASE2
-
Escalated Dose of Irinotecan in mCRC
NCT02256800 ·Status: COMPLETED ·Phase: NA
-
Sorafenib in Combination With Irinotecan in Metastatic Colorectal Cancer Patients With KRAS Mutated Tumors
NCT01715441 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of Everolimus in Patients With Metastatic Colorectal Cancer Who Have Failed Prior Targeted Therapy and Chemotherapy
NCT00419159 ·Status: COMPLETED ·Phase: PHASE2
-
An Open Label Phase II Study of Indisulam in Combination With Irinotecan in Patients With Metastatic Colorectal Cancer Who Have Been Previously Treated With 5-Fluorouracil/Leucovorin and Oxaliplatin
NCT00165867 ·Status: COMPLETED ·Phase: PHASE2
-
Temsirolimus and Irinotecan for Treatment Resistant Patients With Metastatic Colorectal Cancer and KRAS Mutations
NCT00827684 ·Status: COMPLETED ·Phase: PHASE2
-
SarCNU in Treating Patients With Recurrent or Metastatic Colorectal Cancer
NCT00028015 ·Status: COMPLETED ·Phase: PHASE2
-
Drug Trial to Investigate the Safety and Efficacy of Niclosamide Tablets in Patients With Metastases of a Colorectal Cancer Progressing After Therapy
NCT02519582 ·Status: UNKNOWN ·Phase: PHASE2
-
Irinotecan and Cediranib in Treating Patients With Metastatic Colorectal Cancer That Did Not Respond to Previous Oxaliplatin, Fluoropyrimidine, and Bevacizumab
NCT00588900 ·Status: TERMINATED ·Phase: PHASE2
-
Irinotecan in Treating Patients With Metastatic Colorectal Cancer
NCT00003544 ·Status: COMPLETED ·Phase: PHASE2
-
Savolitinib in Treating Patients With MET Amplified Metastatic or Unresectable Colorectal Cancer
NCT03592641 ·Status: TERMINATED ·Phase: PHASE2
-
Study of Irinotecan and AZD1775, a Selective Wee 1 Inhibitor, in RAS or BRAF Mutated, Second-line Metastatic Colorectal Cancer
NCT02906059 ·Status: COMPLETED ·Phase: PHASE1