ABT-751 in Treating Young Patients With Refractory Solid Tumors
NCT00036959 · Status: COMPLETED · Phase: PHASE1 · Type: INTERVENTIONAL · Enrollment: 90
Last updated 2012-03-15
Summary
RATIONALE: Drugs used in chemotherapy, such as ABT-751, work in different ways to stop tumor cells from dividing so they stop growing or die.
PURPOSE: This phase I trial is studying the side effects of ABT-751 in treating young patients with refractory solid tumors.
Conditions
- Brain and Central Nervous System Tumors
- Childhood Germ Cell Tumor
- Extragonadal Germ Cell Tumor
- Kidney Cancer
- Liver Cancer
- Neuroblastoma
- Ovarian Cancer
- Sarcoma
- Unspecified Childhood Solid Tumor, Protocol Specific
Interventions
- DRUG
-
ABT-751
Sponsors & Collaborators
-
National Cancer Institute (NCI)
collaborator NIH -
National Institutes of Health Clinical Center (CC)
lead NIH
Principal Investigators
-
Elizabeth Fox, MD · National Cancer Institute (NCI)
Study Design
- Purpose
- TREATMENT
- Masking
- NONE
Eligibility
- Max Age
- 18 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2002-03-31
- Primary Completion
- 2010-02-28
- Completion
- 2010-02-28
Countries
- United States
Study Locations
More Related Trials
-
ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors
NCT00946335 ·Status: COMPLETED ·Phase: PHASE1
-
Rituximab, Rasburicase, and Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Advanced B-Cell Leukemia or Lymphoma
NCT00057811 ·Status: COMPLETED ·Phase: PHASE2
-
Gemcitabine in Treating Children With Relapsed or Refractory Acute Lymphoblastic Leukemia or Acute Myelogenous Leukemia
NCT00006462 ·Status: COMPLETED ·Phase: PHASE2
-
Topotecan Hydrochloride in Treating Children With Meningeal Cancer That Has Not Responded to Previous Treatment
NCT00005811 ·Status: COMPLETED ·Phase: PHASE2
-
Gemcitabine in Treating Children With Refractory Solid Tumors
NCT00005577 ·Status: COMPLETED ·Phase: PHASE1
-
A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors
NCT00994071 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Efficacy of Cabazitaxel in Pediatric Patients With Refractory Solid Tumors Including Central Nervous System Tumors
NCT01751308 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Temozolomide and O6-benzylguanine in Treating Children With Solid Tumors
NCT00020150 ·Status: COMPLETED ·Phase: PHASE1
-
Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors
NCT02095132 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Total Therapy XVII for Newly Diagnosed Patients With Acute Lymphoblastic Leukemia and Lymphoma
NCT03117751 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2/PHASE3
-
Fenretinide in Treating Children With Solid Tumors
NCT00003191 ·Status: COMPLETED ·Phase: PHASE1
-
Irinotecan in Treating Children With Refractory or Progressive Solid Tumors
NCT00016861 ·Status: COMPLETED ·Phase: PHASE1
-
Tanespimycin in Treating Young Patients With Recurrent or Refractory Leukemia or Solid Tumors
NCT00093821 ·Status: COMPLETED ·Phase: PHASE1
-
Phase I and Pharmacokinetic Trial of Phenylbutyrate Given as a Continuous Infusion in Pediatric Patients With Refractory Malignancy
NCT00001565 ·Status: COMPLETED ·Phase: PHASE1
-
Irinotecan in Treating Young Patients With Refractory or Recurrent Hepatoblastoma
NCT00287976 ·Status: UNKNOWN ·Phase: PHASE2
-
Carboplatin and Irinotecan in Treating Children With Refractory Solid Tumors
NCT00024284 ·Status: COMPLETED ·Phase: PHASE1
-
17-N-Allylamino-17-Demethoxygeldanamycin in Treating Young Patients With Relapsed or Refractory Solid Tumors or Leukemia
NCT00079404 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Test the Safety of the Investigational Drug Selitrectinib in Children and Adults That May Treat Cancer
NCT03215511 ·Status: COMPLETED ·Phase: PHASE1
-
Bortezomib in Treating Children With Advanced Solid Tumors
NCT00021216 ·Status: COMPLETED ·Phase: PHASE1
-
Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors
NCT00788125 ·Status: TERMINATED ·Phase: PHASE1/PHASE2
-
Induction Therapy Including 131 I-MIBG and Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Undergoing Stem Cell Transplant, Radiation Therapy, and Maintenance Therapy With Isotretinoin
NCT01175356 ·Status: COMPLETED ·Phase: PHASE1
-
Intensive Chemo-Radiotherapy With Peripheral Blood Progenitor Cell Rescue for Children With Advanced Neuroblastoma and Sarcomas
NCT00165139 ·Status: COMPLETED ·Phase: PHASE2
-
Combination Chemotherapy in Treating Young Patients With Recurrent or Resistant Malignant Germ Cell Tumors
NCT00467051 ·Status: COMPLETED ·Phase: PHASE2
-
Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)
NCT03126916 ·Status: RECRUITING ·Phase: PHASE3
-
A Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including Neuroblastoma
NCT04238819 ·Status: COMPLETED ·Phase: PHASE1/PHASE2