A Randomized Trial to Reduce the Disparity in Live Donor Kidney Transplantation

Summary

The main purpose of this study is to learn which educational method is most helpful to patients and their family members when they consider whether to pursue live donor kidney transplantation.

Patients who are eligible for a kidney transplant usually get information in the transplant clinic about two types of kidney transplants - one where the kidney comes from a dead donor and one where the kidney comes from a healthy living donor. Patients are given this information by a transplant nurse or doctor and then encouraged to discuss it with family members and friends.

In this study, we are trying to see if changing how and where we give patients this information makes a difference in how patients and their family members think about live donor kidney transplantation. So, we are looking at whether getting the information in the transplant clinic - either alone or in a group - is the same or different than getting the same information in your home.

The study is only recruiting African American patients. This is being done because African Americans have a higher likelihood of developing chronic kidney disease and needing a kidney transplant than patients of other races. However, they wait longer for a kidney transplant and die at a higher rate on the waiting list because they are less likely than other patients to receive a live donor kidney transplant. We want to see which educational approach works best with African American patients and their families.

Conditions

• Chronic Kidney Disease
• End-stage Renal Disease

Interventions

BEHAVIORAL

Group-Based (GB) Intervention

60-minute group session involving other study patients who have been assigned to this condition and their guests.

BEHAVIORAL

Home-Based (HB) Intervention

60-minute educational intervention in their home, which will be delivered by an African American health educator.

Sponsors & Collaborators

• National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

  collaborator NIH

• Beth Israel Deaconess Medical Center

  lead OTHER

Principal Investigators

• James R Rodrigue, Ph.D. · Beth Israel Deaconess Medical Center

• Martha Pavlakis, MD · Beth Israel Deaconess Medical Center

• Didier Mandelbrot, MD · Beth Israel Deaconess Medical Center

• Ogo Egbuna, MD · Beth Israel Deaconess Medical Center

Study Design

Allocation

RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

DOUBLE

Model

PARALLEL

Eligibility

Min Age

21 Years

Max Age

80 Years

Sex

ALL

Healthy Volunteers

No

Timeline & Regulatory

Start

2007-08-31

Primary Completion

2015-11-30

Completion

2020-06-30

Countries

• United States

Study Locations