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The Role of B Cells in Kidney Allograft Dysfunction

NCT02294032 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 180

Last updated 2023-05-19

No results posted yet for this study

Summary

The purpose of this study is to understand the role of specific B cells in activating or repressing an anti-allograft immune response after kidney transplantation. In this study, blood will be collected from kidney transplant patients during different timepoints, prior to and after their transplant. Knowledge gained from study findings will be used to develop therapeutic strategies to prevent antibody-mediated rejection, which is a major cause of long-term graft loss in kidney transplant patients.

Conditions

  • Kidney; Complications, Allograft
  • Transplantation Infection

Interventions

DRUG

Immunosuppressive Agents

standard of care for patients post-transplant

Sponsors & Collaborators

  • Loma Linda University

    lead OTHER

Principal Investigators

  • Michael de Vera, MD, FACS · Loma Linda University Medical Center

Eligibility

Min Age
2 Years
Max Age
85 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2014-08-28
Primary Completion
2023-04-24
Completion
2023-04-24

Countries

  • United States

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT02294032 on ClinicalTrials.gov