Electrophysiologic Measures of Treatment Response in Alzheimer Disease
NCT00018278 · Status: COMPLETED · Phase: PHASE4 · Type: INTERVENTIONAL
Last updated 2009-01-21
Summary
The main purpose of this study is to determine the electrophysiological effects of cholinergic therapy (cholinesterase inhibitors and transdermal nicotine) in Alzheimer disease. The attempt will be to locate electrophysiological markers and predictors of cognitive and clinical treatment response.
Conditions
- Alzheimer Disease
Interventions
- DRUG
-
Aricept
- DRUG
-
Exelon
- DRUG
-
Nicoderm Patch
Sponsors & Collaborators
-
US Department of Veterans Affairs
lead FED
Principal Investigators
-
Vincente Iragui, M.D., Ph.D
-
Shuanna Morris, Ph.D.
Study Design
- Allocation
- NON_RANDOMIZED
- Purpose
- TREATMENT
- Masking
- NONE
- Model
- CROSSOVER
Eligibility
- Min Age
- 55 Years
- Max Age
- 85 Years
- Sex
- ALL
- Healthy Volunteers
- Yes
Timeline & Regulatory
- Start
- 1998-10-31
- Completion
- 2001-09-30
Countries
- United States
Study Locations
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