Efficacy Study of MPC-7869 to Treat Patients With Alzheimer's
NCT00105547 · Status: COMPLETED · Phase: PHASE3 · Type: INTERVENTIONAL · Enrollment: 1600
Last updated 2009-05-05
Summary
The purpose of the study is to evaluate the change in cognitive ability and activities of daily living in patients with Alzheimer's disease (AD) as measured by specific evaluations during 18 months of dosing.
Conditions
- Alzheimer Disease
- Dementia
Interventions
- DRUG
-
MPC-7869
oral 800 mg BID
- DRUG
-
MPC-7869
Oral BID dosing
Sponsors & Collaborators
-
Myrexis Inc.
lead INDUSTRY
Principal Investigators
-
Ed Swabb, MD · Myrexis Inc.
Study Design
- Allocation
- RANDOMIZED
- Purpose
- TREATMENT
- Masking
- TRIPLE
- Model
- PARALLEL
Eligibility
- Min Age
- 55 Years
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2005-02-28
- Completion
- 2008-05-31
Countries
- United States
Study Locations
More Related Trials
-
Efficacy and Safety of T-817MA in Patients With Mild to Moderate Alzheimer's Disease
NCT00663936 ·Status: COMPLETED ·Phase: PHASE2
-
Clinical Pharmacology of p38 MAP Kinase Inhibitor, VX-745, in Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD
NCT02423200 ·Status: COMPLETED ·Phase: PHASE2
-
Multiple IV Dose Study Of PF-04360365 In Patients With Mild To Moderate Alzheimer's Disease
NCT00722046 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of Memantine in Moderate to Severe Alzheimer's Disease
NCT00857649 ·Status: TERMINATED ·Phase: PHASE3
-
SGS742 in Patients With Mild to Moderate Alzheimer's Disease (AD)
NCT00093951 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy of MEM 1003 Versus Placebo in Patients With Mild to Moderate Alzheimer's Disease
NCT00257673 ·Status: COMPLETED ·Phase: PHASE2
-
A Study of the Safety, Tolerability, and Pharmacodynamics of MK-8931 in Participants With Alzheimer's Disease (MK-8931-010 AM1 [P07820 AM1])
NCT01496170 ·Status: COMPLETED ·Phase: PHASE1
-
Safety and Efficacy of TRx0237 in Subjects With Alzheimer's Disease Followed by Open-Label Treatment
NCT03446001 ·Status: COMPLETED ·Phase: PHASE3
-
A Phase I, Single IV Dose Of PF-04360365 In Adults With Mild To Moderate Alzheimer's Disease
NCT00455000 ·Status: COMPLETED ·Phase: PHASE1
-
Effect of Memantine on Functional Communication in Patients With Alzheimer's Disease
NCT00469456 ·Status: COMPLETED ·Phase: PHASE4
-
Preliminary Efficacy and Safety Study of ST101 in Alzheimer's Disease
NCT00842673 ·Status: COMPLETED ·Phase: PHASE2
-
Piromelatine 20 mg in Participants With Mild Dementia Due to Alzheimer's Disease
NCT05267535 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2/PHASE3
-
The Safety and Efficacy of an Investigational Drug in Delaying the Progression of Alzheimer's Disease
NCT00006187 ·Status: TERMINATED ·Phase: PHASE3
-
Efficacy and Safety of S18986 in the Treatment of Mild Cognitive Impairment Patients
NCT00202540 ·Status: TERMINATED ·Phase: PHASE2
-
Open-Label Treatment With MPC-7869 for Patients With Alzheimer's Who Previously Participated in an MPC-7869 Protocol
NCT00380276 ·Status: TERMINATED ·Phase: PHASE3
-
Efficacy and Safety of 26-Week Treatment of AR1001 in Patients With Mild to Moderate Alzheimer's Disease
NCT03625622 ·Status: COMPLETED ·Phase: PHASE2
-
Study of the Effect of SR57667B in Patients With Alzheimer's Disease
NCT00285025 ·Status: COMPLETED ·Phase: PHASE2
-
A Study to Evaluate the Safety and Efficacy of CT1812 in Subjects With Mild to Moderate Alzheimer's Disease.
NCT03507790 ·Status: COMPLETED ·Phase: PHASE2
-
A Multiple Dose Study of PF-04360365 In Patients With Mild to Moderate Alzheimer's Disease
NCT00945672 ·Status: COMPLETED ·Phase: PHASE2
-
Efficacy and Safety of AD-35 in Treatment of Subjects With Mild to Moderate Alzheimer's Disease
NCT03625401 ·Status: UNKNOWN ·Phase: PHASE2
-
A Study to Evaluate the Effects of SAGE-718 in Participants With Mild Cognitive Impairment or Mild Dementia Due to Alzheimer's Disease (AD)
NCT05619692 ·Status: COMPLETED ·Phase: PHASE2
-
Safety and Efficacy Study Evaluating TRx0237 in Subjects With Mild to Moderate Alzheimer's Disease
NCT01689246 ·Status: COMPLETED ·Phase: PHASE3
-
Biomarker Predictors of Memantine Sensitivity in Patients With Alzheimer's Disease
NCT03703856 ·Status: COMPLETED ·Phase: PHASE4
-
Study to Evaluate DNL747 in Subjects With Alzheimer's Disease
NCT03757325 ·Status: COMPLETED ·Phase: PHASE1
-
Cognition Platform Study in Participants at Risk for Alzheimer's Disease (AD) (MK-0000-413)
NCT04730635 ·Status: COMPLETED ·Phase: PHASE1