Study of Arthritis and Related Conditions
NCT00006333 · Status: COMPLETED · Type: OBSERVATIONAL · Enrollment: 697
Last updated 2021-03-12
Summary
This research protocol will recruit patients with arthritis and related conditions for the purpose of screening patients for treatment protocols, and evaluating the natural history of arthritis and related conditions. Patients will be evaluated clinically, radiographically and serologically, and standardized data will be uniformly collected on all patients. Additional imaging using sensitive MRI methods will be obtained in some patients. The collected blood and tissue will be utilized for laboratory studies to continue research on the pathogenic mechanisms of rheumatoid arthritis and related autoimmune joint diseases. Data from the history and physical examination as well as several disability questionnaires in the adult and pediatric population will be used to phenotypically characterize these patients and assess outcome and functional status. Any medical care recommended or provided to the patients will be consistent with routine standards of practice and provided in consultation with the patient's referring physician.
Conditions
Sponsors & Collaborators
-
National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
lead NIH
Principal Investigators
-
James D Katz, M.D. · National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Eligibility
- Sex
- ALL
- Healthy Volunteers
- No
Timeline & Regulatory
- Start
- 2000-10-03
- Primary Completion
- 2021-03-10
- Completion
- 2021-03-10
Countries
- United States
Study Locations
More Related Trials
-
Treatment of TNFa Naive Patients With Poor Prognosis Rheumatoid Arthritis
NCT00963703 ·Status: COMPLETED ·Phase: NA
-
Dose-finding of Multiple Dose of BT061 in Patients With Active Rheumatoid Arthritis Incompletely Controlled on Stable Methotrexate (MTX)
NCT01481493 ·Status: COMPLETED ·Phase: PHASE2
-
A Retrospective Observational Study on the Use of Biologics in Monotherapy in Patients With Rheumatoid Arthritis
NCT01834807 ·Status: COMPLETED
-
A Study to Evaluate BioMarkers in Blood Samples in Subjects With Rheumatoid Arthritis
NCT01209585 ·Status: COMPLETED
-
The Role of IL-23 in Chronic Inflammatory Disease: Exploring the Cellular and Molecular Targets of IL-23 Signaling in Peripheral and Axial Spondyloarthritis
NCT05290363 ·Status: RECRUITING ·Phase: NA
-
Impact of Rituximab on MRI Evidence of Disease Activity in Patients With Moderate to Severe Rheumatoid Arthritis
NCT00425932 ·Status: COMPLETED ·Phase: PHASE2
-
A Phase 3 Study of NI-071 in Patients With Rheumatoid Arthritis
NCT01927263 ·Status: COMPLETED ·Phase: PHASE3
-
A Trial of NNC0109-0012, an Anti-IL-20 Biologic, in Patients With Active Rheumatoid Arthritis Who Are Inadequate Responders to Anti-TNFa Biologics
NCT01636817 ·Status: TERMINATED ·Phase: PHASE2
-
Study Evaluating Multiple Doses Of ATN-103 In Subjects With Active Rheumatoid Arthritis
NCT00959036 ·Status: COMPLETED ·Phase: PHASE1/PHASE2
-
Study to Determine the Effects of Different Doses of Methotrexate (MTX) When Taken With Adalimumab in Subjects With Early Rheumatoid Arthritis (RA)
NCT01185301 ·Status: COMPLETED ·Phase: PHASE3
-
Anti-TNF Agents for the Treatment of Rheumatoid Arthritis
NCT00837434 ·Status: COMPLETED ·Phase: PHASE4
-
A Study of the Safety of Rituximab in Combination With Other Anti-Rheumatic Drugs in Subjects With Active Rheumatoid Arthritis
NCT00443651 ·Status: COMPLETED ·Phase: PHASE3
-
Long-term Safety and Efficacy of Sirukumab in Participants With RA Completing Studies CNTO136ARA3002 or CNTO136ARA3003
NCT01856309 ·Status: COMPLETED ·Phase: PHASE3
-
A Phase II Trial of SHR-3045 Injection in Patients With Rheumatoid Arthritis
NCT07233655 ·Status: ACTIVE_NOT_RECRUITING ·Phase: PHASE2
-
A Study to Evaluate the Effectiveness of Infliximab and Changes in Hand and Wrist Magnetic Resonance Imaging (MRI) in Participants With Active Rheumatoid Arthritis (RA) (P08136)
NCT01313520 ·Status: COMPLETED ·Phase: PHASE2
-
Evaluation of the Condition of Rheumatoid Arthritis After Treatment
NCT02157012 ·Status: UNKNOWN ·Phase: PHASE4
-
Study of SHR0302 Tablets (SHR0302) as Monotherapy in Active Rheumatoid Arthritis (RA) Patients
NCT03254966 ·Status: COMPLETED ·Phase: PHASE2
-
Extension Study to Assess the Efficacy and Safety of Repeat Treatment With Rituximab (MabThera) in Participants With Active Rheumatoid Arthritis (RA)
NCT02093026 ·Status: COMPLETED ·Phase: PHASE2
-
Study Evaluating Long-Term Safety Of ATN-103 In Subjects With Rheumatoid Arthritis
NCT01063803 ·Status: COMPLETED ·Phase: PHASE2
-
Mechanism of Action of Anti-IL17 Therapy in Peripheral Spondyloarthritis
NCT03358134 ·Status: COMPLETED ·Phase: PHASE3
-
Study of LX3305 and Methotrexate in Subjects With Stable Rheumatoid Arthritis
NCT00847886 ·Status: COMPLETED ·Phase: PHASE1
-
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of Multiple Subcutaneous Injections of ABT-122 in Subjects With Rheumatoid Arthritis
NCT01853033 ·Status: COMPLETED ·Phase: PHASE1
-
Infliximab for the Treatment of Early Rheumatoid Arthritis
NCT00006292 ·Status: COMPLETED ·Phase: PHASE2
-
IL-6, IL-12, IL-15 and IL-23 Expression Levels in Rheumatoid Arthritis Patients
NCT06558305 ·Status: NOT_YET_RECRUITING
-
A Study of Retreatment With Rituximab in Patients With Rheumatoid Arthritis Receiving Background Methotrexate
NCT00266227 ·Status: COMPLETED ·Phase: PHASE3