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Axial Involvement in Psoriatic Arthritis Cohort

NCT04434885 · Status: UNKNOWN · Type: OBSERVATIONAL · Enrollment: 400

Last updated 2022-06-27

No results posted yet for this study

Summary

This is a multinational multicenter cross-sectional study in patients with a definite diagnosis of PsA. The population of interest will consist of 400 adult patients diagnosed with PsA and fulfilling the classification criteria for PsA and not receiving biological or targeted synthetic disease modifying antirheumatic drugs (b or tsDMARDs). Participating rheumatologists are encouraged to include consecutive PsA patients not treated with biologic or a targeted synthetic disease-modifying antirheumatic drug because of their potential impact on active inflammatory changes in the axial skeleton, which will be the focus of the current study. Patients will be recruited prospectively in selected study centres and will undergo study-related examinations including imaging of the axial skeleton (X-rays and magnetic resonance imaging). Collected data will serve as a basis for the judgement on the presence or absence of axial involvement by the local investigator and, independently, by the central study committee.

Conditions

Interventions

OTHER

Clinical and imaging examination of symptoms and signs suggestive of axial involvement

Clinical and imaging examination including X-rays and magnetic resonance imaging of sacroiliac joints and spine

Sponsors & Collaborators

  • Assessment of Spondyloarthritis International Society (ASAS)

    collaborator UNKNOWN

  • Group for Research and Assessment of Psoriasis and Psoriatic Arthritis

    collaborator NETWORK

  • Charite University, Berlin, Germany

    lead OTHER

Principal Investigators

  • Denis Poddubnyy, MD · Charite University, Berlin, Germany

  • Dafna D. Gladman, MD, FRCPC · University of Toronto

Eligibility

Sex
ALL
Healthy Volunteers
No

Timeline & Regulatory

Start
2021-07-01
Primary Completion
2023-12-31
Completion
2023-12-31

Countries

  • Canada
  • Germany

Study Locations

More Related Trials

Entities

Diseases

Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT04434885 on ClinicalTrials.gov